SCHEMBL10339804

SCHEMBL10339804

CC(OC(=O)/C=C/C(=O)O)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 6/20 1.00
TAAR1 Q96RJ0 1/20 0.41
ALDH1A1 P00352 2/20 0.40
TP53 P04637 1/20 0.40
HSD17B10 Q99714 1/20 0.40
KDM4E B2RXH2 3/20 0.40
POLB P06746 1/20 0.40
MAPT P10636 2/20 0.40
MAPK1 P28482 1/20 0.40
MDM4 O15151 1/20 0.39
LMNA P02545 1/20 0.39
MDM2 Q00987 1/20 0.39
KMT2A Q03164 1/20 0.39
LTB4R Q15722 1/20 0.39
LTB4R2 Q9NPC1 1/20 0.39
FFAR1 O14842 1/20 0.39
HDAC3 O15379 1/20 0.38
TNKS O95271 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC1 Q13547 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17868324 1.00 HCAR2 (1.00) HCAR2TAAR1ALDH1A1TP53HSD17B10
SCHEMBL573378 1.00 HCAR2 (1.00) HCAR2TAAR1ALDH1A1TP53HSD17B10
SCHEMBL573375 0.94 HCAR2 (0.89) HCAR2ALDH1A1TP53HSD17B10MAPT
SCHEMBL10339803 0.94 HCAR2 (0.89) HCAR2ALDH1A1TP53HSD17B10MAPT
Maleic Acid SCHEMBL27844223 0.88 HCAR2 (0.79) HCAR2TAAR1ALDH1A1TP53HSD17B10
SCHEMBL8872000 0.86 HCAR2 (0.76) HCAR2ALDH1A1TP53HSD17B10MAPT
SCHEMBL1845408 0.86 HCAR2 (0.75) HCAR2ALDH1A1TP53HSD17B10KMT2A
SCHEMBL1845412 0.86 HCAR2 (0.75) HCAR2ALDH1A1TP53HSD17B10KMT2A
Cinnamic Acid SCHEMBL28334048 0.85 HCAR2 (0.74) HCAR2ALDH1A1KDM4EMAPTMAPK1
SCHEMBL43630 0.83 HCAR2 (0.71) HCAR2ALDH1A1MAPTLMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101346341-A Improvements in or related to organic compoounds GIVAUDAN SA (CH) 2009-01-14 CN claimed
JP-2269708-A None JP disclosed
CN-112203833-B Automatic injection method for mold of monomer for optical material 可奥熙搜路司有限公司 2022-11-25 CN disclosed
CN-112203833-A Automatic injection method for mold of monomer for optical material 可奥熙搜路司有限公司 2021-01-08 CN disclosed
CN-101346341-A Improvements in or related to organic compoounds GIVAUDAN SA (CH) 2009-01-14 CN disclosed
JP-H02269708-A PRODUCTION OF VINYL CHLORIDE COPOLYMER NIPPON SHOKUBAI KAGAKU KOGYO CO LTD 1990-11-05 JP disclosed