⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16797801 | 0.69 | — | — | |
| SCHEMBL15875039 | 0.67 | — | — | |
| SCHEMBL6402944 | 0.66 | — | — | |
| SCHEMBL223818 | 0.59 | — | — | |
| SCHEMBL20801056 | 0.59 | — | — | |
| SCHEMBL12509850 | 0.50 | — | — | |
| SCHEMBL4817 | 0.47 | — | — | |
| Aziridine SCHEMBL2267 | 0.47 | — | — | |
| Aziridine SCHEMBL16878816 | 0.47 | — | — | |
| SCHEMBL130460 | 0.47 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240217988-A1 | ESTROGEN RECEPTOR ANTAGONIST | SHENZHEN FORWARD PHARMACEUTICALS CO., LIMITED (CN) | 2024-07-04 | — | — | US | claimed |
| EP-4393922-A1 | IRAK4 DEGRADATION AGENT, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Leadingtac Pharmaceutical Co. Ltd. (CN) | 2024-07-03 | — | — | EP | claimed |
| EP-4328219-A1 | SOS1 DEGRADING AGENT AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shanghai Leadingtac Pharmaceutical Co. Ltd. (CN) | 2024-02-28 | — | — | EP | claimed |
| EP-4310079-A1 | ESTROGEN RECEPTOR ANTAGONIST | Shenzhen Forward Pharmaceuticals Co., Limited (CN) | 2024-01-24 | — | — | EP | claimed |
| CN-115745963-A | Protein degradation compound based on NAMPT target protein and application thereof | 标新生物医药科技(上海)有限公司 | 2023-03-07 | — | — | CN | claimed |
| CN-115667239-A | Substituted pyrazines, pharmaceutical compositions comprising them and their use | 四川科伦博泰生物医药股份有限公司 | 2023-01-31 | — | — | CN | claimed |
| US-20220135557-A1 | RET INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2022-05-05 | — | — | US | claimed |
| US-20220119382-A1 | RET INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2022-04-21 | — | — | US | claimed |
| CN-112142711-B | Substituted thiophene compound, preparation method and application thereof | 中国科学院上海药物研究所 | 2022-03-29 | — | — | CN | claimed |
| CN-113582980-A | Compound based on heterocyclic ring and glutarimide framework and application thereof | 上海科技大学 | 2021-11-02 | — | — | CN | claimed |
| EP-3891148-A1 | RET INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2021-10-13 | — | — | EP | claimed |
| EP-3891149-A1 | RET INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2021-10-13 | — | — | EP | claimed |
| CN-105611930-B | Spiro quinoxaline derivatives as non-apoptotic regulated cell death inhibitors | 亥姆霍兹慕尼黑中心-德国环境与健康研究中心（股份有限公司） | 2021-03-02 | — | — | CN | claimed |
| CN-112142711-A | Substituted thiophene compound, preparation method and application thereof | 中国科学院上海药物研究所 | 2020-12-29 | — | — | CN | claimed |
| CN-111285874-A | RET inhibitors, pharmaceutical compositions thereof and uses thereof | 广东东阳光药业有限公司 | 2020-06-16 | — | — | CN | claimed |
| CN-111285873-A | RET inhibitors, pharmaceutical compositions thereof and uses thereof | 广东东阳光药业有限公司 | 2020-06-16 | — | — | CN | claimed |
| WO-2020114487-A1 | RET INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2020-06-11 | — | — | WO | claimed |
| WO-2020114494-A1 | RET INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2020-06-11 | — | — | WO | claimed |
| EP-3660023-A1 | COMPOUND AS ACC INHIBITOR AND USE THEREOF | Nanjing Sanhome Pharmaceutical Co., Ltd. (CN) | 2020-06-03 | — | — | EP | claimed |
| US-20200165265-A1 | COMPOUND AS ACC INHIBITOR AND USE THEREOF | NANJING SANHOME PHARMACEUTICAL CO., LTD. (CN) | 2020-05-28 | — | — | US | claimed |