Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B17 | O75795 | 2/20 | 0.47 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.46 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30109346 | 0.89 | MAP3K14 (0.47) | UGT2B17MAP3K14KCNH2 | |
| SCHEMBL7096349 | 0.89 | MAP3K14 (0.47) | UGT2B17MAP3K14KCNH2 | |
| SCHEMBL13646649 | 0.86 | UGT2B17 (0.43) | UGT2B17MAP3K14BRD3 | |
| SCHEMBL5750720 | 0.80 | UGT2B17 (0.38) | UGT2B17MAP3K14BRD3GAAHSD17B10 | |
| SCHEMBL26910499 | 0.77 | HRH3 (0.37) | UGT2B17MAP3K14ACHE | |
| SCHEMBL23142120 | 0.75 | MAP3K14 (0.39) | UGT2B17MAP3K14CYP1A2 | |
| SCHEMBL15276006 | 0.75 | MAP3K14 (0.39) | UGT2B17MAP3K14 | |
| SCHEMBL23142099 | 0.75 | MAP3K14 (0.39) | UGT2B17MAP3K14CYP1A2 | |
| SCHEMBL12507000 | 0.75 | MAP3K14 (0.50) | UGT2B17MAP3K14ALDH1A1 | |
| SCHEMBL23142126 | 0.75 | MAP3K14 (0.39) | UGT2B17MAP3K14CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0157436-B1 | PERFUME COMPOSITIONS AND PERFUMED ARTICLES CONTAINING DIHYDRO- AND/OR TETRAHYDRO-NAPHTOLS AS FRAGRANCE MATERIAL | NAARDEN INTERNATIONAL N.V. (NL) | 1990-01-03 | — | — | EP | disclosed |
| US-4643844-A | LEATHER ODOR | 501 Naarden International N.V. (NL) | 1987-02-17 | — | — | US | disclosed |
| EP-0157436-A1 | Perfume compositions and perfumed articles containing dihydro- and/or tetrahydro-naphtols as fragrance material | NAARDEN INTERNATIONAL N.V. (NL) | 1985-10-09 | — | — | EP | disclosed |