Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10340276 | 1.00 | NPC1 (0.43) | NPC1RAB9AMAPTTDP1TSHR | |
| SCHEMBL21807366 | 0.85 | HDAC3 (0.46) | NPC1RAB9AMAPTTSHRALDH1A1 | |
| SCHEMBL28250865 | 0.85 | HDAC3 (0.46) | NPC1RAB9AMAPTTSHRALDH1A1 | |
| SCHEMBL27159397 | 0.83 | PPARA (0.41) | NPC1RAB9AMAPTTSHRALDH1A1 | |
| SCHEMBL27159394 | 0.83 | PPARA (0.41) | NPC1RAB9AMAPTTSHRALDH1A1 | |
| SCHEMBL1970964 | 0.81 | MAPT (0.49) | NPC1RAB9AMAPTTDP1ALDH1A1 | |
| SCHEMBL1969125 | 0.81 | MAPT (0.49) | NPC1RAB9AMAPTTDP1ALDH1A1 | |
| SCHEMBL1969127 | 0.81 | MAPT (0.49) | NPC1RAB9AMAPTTDP1ALDH1A1 | |
| SCHEMBL28250847 | 0.81 | NPC1 (0.53) | NPC1RAB9AMAPTTDP1ALDH1A1 | |
| SCHEMBL8351698 | 0.79 | ACACB (0.49) | NPC1RAB9AMAPTTDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2306944-A | — | — | None | — | — | JP | disclosed |
| JP-H02306944-A | PRODUCTION OF OPTICALLY ACTIVE 1-(P-BROMOPHENYL) ETHYLAMINE | TORAY IND INC | 1990-12-20 | — | — | JP | disclosed |