Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 10/20 | 0.41 |
| ▸ | SPHK2 | Q9NRA0 | 9/20 | 0.41 |
| ▸ | RARB | P10826 | 5/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10340464 | 1.00 | MEN1 (0.46) | MEN1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL9817600 | 0.82 | HRH3 (0.47) | MEN1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL9817525 | 0.82 | HRH3 (0.47) | MEN1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL9817441 | 0.82 | HRH3 (0.47) | MEN1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL9436300 | 0.81 | MAPT (0.62) | MEN1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL10340522 | 0.81 | MAPT (0.62) | MEN1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL9436028 | 0.81 | MAPT (0.62) | MEN1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL9436033 | 0.81 | MAPT (0.62) | MEN1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL10340674 | 0.81 | MAPT (0.62) | MEN1ALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL10340352 | 0.81 | MAPT (0.62) | MEN1ALDH1A1MAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0227717-B1 | NITROGEN-CONTAINING HETEROCYCLIC ESTERS | MERCK PATENT GmbH (DE) | 1990-04-25 | — | — | EP | disclosed |
| EP-0224579-B1 | SMECTIC LIQUID CRYSTALLINE PHASES | MERCK PATENT GmbH (DE) | 1990-01-24 | — | — | EP | disclosed |
| EP-0227717-A1 | NITROGEN-CONTAINING HETEROCYCLIC ESTERS. | MERCK PATENT GMBH (DE) | 1987-07-08 | — | — | EP | disclosed |
| EP-0224579-A1 | SMECTIC LIQUID CRYSTALLINE PHASES. | MERCK PATENT GMBH (DE) | 1987-06-10 | — | — | EP | disclosed |
| WO-1986007085-A1 | SMECTIC LIQUID CRYSTALLINE PHASES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1986-12-04 | — | — | WO | disclosed |
| WO-1986007055-A1 | NITROGEN-CONTAINING HETEROCYCLIC ESTERS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1986-12-04 | — | — | WO | disclosed |