⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992582 | 0.78 | — | — | |
| SCHEMBL4126187 | 0.76 | — | — | |
| SCHEMBL20845555 | 0.75 | NOTUM (0.67) | — | |
| SCHEMBL10717593 | 0.74 | VHL (0.37) | — | |
| SCHEMBL27388385 | 0.73 | — | — | |
| SCHEMBL10717714 | 0.73 | CHRM1 (0.35) | — | |
| SCHEMBL10718420 | 0.73 | PPARA (0.36) | — | |
| SCHEMBL5783147 | 0.71 | — | — | |
| SCHEMBL2429368 | 0.71 | — | — | |
| SCHEMBL18346818 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207955-B1 | PROCESS FOR THE PREPARATION OF 3,5-DISUBSTITUTED ISOXAZOLES | ZAMBON S.p.A. (IT) | 1990-02-07 | — | — | EP | disclosed |
| US-4772719-A | FROM DIHALOFORMALDOXIME AND ALKYNE, CYCLIZATION | ZAMBON S.P.A. (IT) | 1988-09-20 | — | — | US | disclosed |
| EP-0207955-A1 | PROCESS FOR THE PREPARATION OF 3,5-DISUBSTITUTED ISOXAZOLES. | ZAMBON SPA (IT) | 1987-01-14 | — | — | EP | disclosed |
| WO-1986003490-A1 | PROCESS FOR THE PREPARATION OF 3,5-DISUBSTITUTED ISOXAZOLES | ZAMBON S.P.A. (IT) | 1986-06-19 | — | — | WO | disclosed |