SCHEMBL10344237

SCHEMBL10344237

CCc1cnc2c(C(=O)O)c(Cl)ccc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALK Q9UM73 1/20 0.56
PARP1 P09874 1/20 0.50
PDE4A P27815 1/20 0.38
PDE4B Q07343 1/20 0.38
PDE4C Q08493 1/20 0.38
PDE4D Q08499 1/20 0.38
DPP4 P27487 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
MRGPRX4 Q96LA9 1/20 0.37
ALDH1A1 P00352 3/20 0.37
KDM4E B2RXH2 1/20 0.37
HSD17B10 Q99714 1/20 0.37
FABP4 P15090 2/20 0.36
FABP5 Q01469 2/20 0.36
GAA P10253 1/20 0.36
HTT P42858 1/20 0.36
GFER P55789 1/20 0.36
SLC22A12 Q96S37 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31490355 1.00 ALK (0.56) ALKPARP1PDE4APDE4BPDE4C
SCHEMBL10356807 0.86 ALK (0.56) ALKPARP1DPP4SMN1; SMN2ALDH1A1
SCHEMBL10593564 0.84 PARP1 (0.46) ALKPARP1PDE4APDE4BPDE4C
SCHEMBL10764820 0.83 PARP1 (0.50) ALKPARP1NPC1RAB9ASMN1; SMN2
Quinmerac SCHEMBL29433226 0.81 ALK (0.60) ALKPARP1DPP4NPC1RAB9A
Quinmerac SCHEMBL8539662 0.81 ALK (0.60) ALKPARP1DPP4NPC1RAB9A
Quinmerac SCHEMBL54128 0.81 ALK (0.60) ALKPARP1DPP4NPC1RAB9A
Quinmerac SCHEMBL29351452 0.81 ALK (0.60) ALKPARP1DPP4NPC1RAB9A
Quinclorac SCHEMBL55011 0.80 ALK (0.63) ALKDPP4SMN1; SMN2ALDH1A1KDM4E
Quinclorac SCHEMBL29371402 0.80 ALK (0.63) ALKDPP4SMN1; SMN2ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210033618-A1 BIOLOGICAL STATUS CLASSIFICATION RANDOX LABORATORIES LTD (GB) 2021-02-04 US disclosed
EP-0192111-B1 ISO-UREAS, PROCESSES FOR THEIR PRODUCTION AND THEIR USE AS HERBICIDES BASF Aktiengesellschaft (DE) 1990-05-16 EP disclosed
EP-0270889-B1 USE OF 7-CHLOROQUINOLINE-8-CARBOXYLIC ACIDS FOR INFLUENCING THE DEVELOPMENT OF CROPS BASF Aktiengesellschaft (DE) 1990-05-09 EP disclosed
US-4857103-A Influencing the development of crops with 7-chloroquinoline-8-carboxylic acids BASF AKTIENGESELLSCHAFT (DE) 1989-08-15 US disclosed
EP-0208245-B1 HERBICIDAL AND PLANT GROWTH-REGULATING AGENT BASED ON QUINOLINE DERIVATIVES BASF Aktiengesellschaft (DE) 1989-04-05 EP disclosed
EP-0270889-A1 Use of 7-chloroquinoline-8-carboxylic acids for influencing the development of crops BASF Aktiengesellschaft (DE) 1988-06-15 EP disclosed
EP-0257518-A1 Quinoline-8-carboxylic acid derivatives BASF Aktiengesellschaft (DE) 1988-03-02 EP disclosed
US-4726837-A Use of 4H-pyrido[2,3-d][1,3]oxazin-4-one derivatives for controlling undesirable plant growth BASF AKTIENGESELLSCHAFT (DE) 1988-02-23 US disclosed
US-4715889-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1987-12-29 US disclosed
US-4692187-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1987-09-08 US disclosed
EP-0192111-A1 Iso-ureas, processes for their production and their use as herbicides BASF Aktiengesellschaft (DE) 1986-08-27 EP disclosed
EP-0104389-B1 QUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE CONTROL OF UNDESIRED PLANT GROWTH BASF Aktiengesellschaft (DE) 1986-07-16 EP disclosed
EP-0170203-A2 4H-Pyrido(2,3-d)(1,3)oxazin-4-one derivatives, process for their preparation, and their use for combating undesired vegetation BASF Aktiengesellschaft (DE) 1986-02-05 EP disclosed
EP-0104389-A2 Quinoline derivatives, process for their preparation and their use in the control of undesired plant growth BASF Aktiengesellschaft (DE) 1984-04-04 EP disclosed