SCHEMBL10344673

SCHEMBL10344673

N#Cc1cnn(-c2c(Br)cc(Br)cc2Br)c1N

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.49
MEN1 O00255 2/20 0.49
KDM4E B2RXH2 1/20 0.49
ABL1 P00519 1/20 0.45
KDR P35968 1/20 0.45
XDH P47989 2/20 0.44
ALDH1A1 P00352 2/20 0.38
NPSR1 Q6W5P4 1/20 0.38
HPGD P15428 2/20 0.36
PKM P14618 1/20 0.36
PTGS1 P23219 1/20 0.34
PTGS2 P35354 1/20 0.34
HTT P42858 2/20 0.34
MAPT P10636 2/20 0.34
LPAR1 Q92633 1/20 0.34
GLA P06280 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11276408 0.90 KMT2A (0.43) KMT2AMEN1KDM4EABL1KDR
SCHEMBL17176676 0.88 KMT2A (0.57) KMT2AMEN1KDM4EABL1KDR
SCHEMBL11283714 0.88 KMT2A (0.47) KMT2AMEN1KDM4EABL1KDR
SCHEMBL11268556 0.84 KMT2A (0.47) KMT2AMEN1KDM4EABL1KDR
SCHEMBL840405 0.84 KMT2A (0.55) KMT2AMEN1KDM4EABL1KDR
SCHEMBL10616201 0.84 KDM4E (0.47) KMT2AMEN1KDM4EABL1KDR
SCHEMBL11283693 0.81 KMT2A (0.43) KMT2AMEN1KDM4EABL1KDR
SCHEMBL10620591 0.76 KMT2A (0.55) KMT2AMEN1KDM4EABL1KDR
SCHEMBL4700651 0.75 KMT2A (0.71) KMT2AMEN1KDM4EABL1KDR
SCHEMBL10985964 0.75 KMT2A (0.62) KMT2AMEN1KDM4EABL1KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0053678-A1 5-Amino-1-phenyl-4-cyano pyrazoles, herbicides containing them, process for their preparation and their use as herbicides BASF Aktiengesellschaft (DE) 1982-06-16 EP claimed
EP-0192111-B1 ISO-UREAS, PROCESSES FOR THEIR PRODUCTION AND THEIR USE AS HERBICIDES BASF Aktiengesellschaft (DE) 1990-05-16 EP disclosed
EP-0121129-B1 2,5-DIHYDRO-5-ARYLIMINO-PYRROLES, PROCESS FOR THEIR PRODUCTION AND THEIR USES AS HERBICIDES BASF Aktiengesellschaft (DE) 1989-02-01 EP disclosed
US-4726837-A Use of 4H-pyrido[2,3-d][1,3]oxazin-4-one derivatives for controlling undesirable plant growth BASF AKTIENGESELLSCHAFT (DE) 1988-02-23 US disclosed
US-4715889-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1987-12-29 US disclosed
US-4692187-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1987-09-08 US disclosed
EP-0104389-B1 QUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE CONTROL OF UNDESIRED PLANT GROWTH BASF Aktiengesellschaft (DE) 1986-07-16 EP disclosed
US-4585881-A 2,5-dihydro-5-aryliminopyrrole derivatives and their preparation BASF AKTIENGESELLSCHAFT (DE) 1986-04-29 US disclosed
EP-0170203-A2 4H-Pyrido(2,3-d)(1,3)oxazin-4-one derivatives, process for their preparation, and their use for combating undesired vegetation BASF Aktiengesellschaft (DE) 1986-02-05 EP disclosed
EP-0034945-B1 N-PHENYLPYRAZOLE DERIVATIVES MAY & BAKER LIMITED (GB) 1985-08-07 EP disclosed
US-4496390-A WEED-CONTRTOLLING HERBICIDES MAY & BAKER LIMITED (GB) 1985-01-29 US disclosed
EP-0121129-A1 2,5-Dihydro-5-arylimino-pyrroles, process for their production and their uses as herbicides BASF Aktiengesellschaft (DE) 1984-10-10 EP disclosed
EP-0115808-A1 Cyclohexan-1,3-dione derivatives, process for their preparation and their use as herbicides BASF Aktiengesellschaft (DE) 1984-08-15 EP disclosed
EP-0104389-A2 Quinoline derivatives, process for their preparation and their use in the control of undesired plant growth BASF Aktiengesellschaft (DE) 1984-04-04 EP disclosed
EP-0053678-A1 5-Amino-1-phenyl-4-cyano pyrazoles, herbicides containing them, process for their preparation and their use as herbicides BASF Aktiengesellschaft (DE) 1982-06-16 EP disclosed
EP-0034945-A2 N-phenylpyrazole derivatives MAY & BAKER LIMITED (GB) 1981-09-02 EP disclosed