SCHEMBL10344719

SCHEMBL10344719

O=c1oc(-c2cccc(F)c2)nc2cccc(Cl)c12

nearest known ligand 0.72

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PBRM1 Q86U86 1/20 0.72
ELANE P08246 9/20 0.62
C1R P00736 2/20 0.55
HPN P05981 1/20 0.55
NOTUM Q6P988 1/20 0.46
MAOB P27338 2/20 0.45
ALDH1A1 P00352 1/20 0.42
F2 P00734 1/20 0.42
HPGD P15428 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10344640 0.86 ELANE (0.65) PBRM1ELANEC1RALDH1A1
SCHEMBL10344798 0.86 HPN (0.57) PBRM1ELANEC1RHPNNOTUM
SCHEMBL6246926 0.84 ELANE (0.73) PBRM1ELANEC1RF2
SCHEMBL24743518 0.84 PBRM1 (1.00) PBRM1ELANEC1RNOTUMALDH1A1
SCHEMBL912820 0.83 PBRM1 (0.67) PBRM1ELANEC1RNOTUM
SCHEMBL11000841 0.82 PBRM1 (0.70) PBRM1ELANEC1RNOTUMALDH1A1
SCHEMBL10344903 0.82 PBRM1 (0.66) PBRM1ELANEC1RNOTUMALDH1A1
SCHEMBL10596811 0.80 PBRM1 (0.63) PBRM1ELANEC1RALDH1A1F2
SCHEMBL10344537 0.80 PBRM1 (0.63) PBRM1ELANEC1RALDH1A1F2
SCHEMBL10596923 0.80 PBRM1 (0.63) PBRM1ELANEC1RHPNALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0049398-B1 4H-3,1-BENZOXAZIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES BASF Aktiengesellschaft (DE) 1985-03-06 EP claimed
US-4363651-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1982-12-14 US claimed
EP-0049398-A1 4H-3,1-Benzoxazin derivatives, process for their preparation and their use as herbicides BASF Aktiengesellschaft (DE) 1982-04-14 EP claimed
EP-0192111-B1 ISO-UREAS, PROCESSES FOR THEIR PRODUCTION AND THEIR USE AS HERBICIDES BASF Aktiengesellschaft (DE) 1990-05-16 EP disclosed
US-4726837-A Use of 4H-pyrido[2,3-d][1,3]oxazin-4-one derivatives for controlling undesirable plant growth BASF AKTIENGESELLSCHAFT (DE) 1988-02-23 US disclosed
US-4715889-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1987-12-29 US disclosed
US-4692187-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1987-09-08 US disclosed
US-4673740-A Preparation of substituted 2-phenyl-4H-3,1-benzoxazin-4-ones BASF AKTIENGESELLSCHAFT (DE) 1987-06-16 US disclosed
EP-0199276-A2 Process for preparaing substituted 2-phenyl-4H-3,1-benzoxazin-4-ones BASF Aktiengesellschaft (DE) 1986-10-29 EP disclosed
EP-0192111-A1 Iso-ureas, processes for their production and their use as herbicides BASF Aktiengesellschaft (DE) 1986-08-27 EP disclosed
EP-0115808-B1 CYCLOHEXAN-1,3-DIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES BASF Aktiengesellschaft (DE) 1986-08-20 EP disclosed
EP-0104389-B1 QUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE CONTROL OF UNDESIRED PLANT GROWTH BASF Aktiengesellschaft (DE) 1986-07-16 EP disclosed
US-4585881-A 2,5-dihydro-5-aryliminopyrrole derivatives and their preparation BASF AKTIENGESELLSCHAFT (DE) 1986-04-29 US disclosed
EP-0170203-A2 4H-Pyrido(2,3-d)(1,3)oxazin-4-one derivatives, process for their preparation, and their use for combating undesired vegetation BASF Aktiengesellschaft (DE) 1986-02-05 EP disclosed
EP-0049398-B1 4H-3,1-BENZOXAZIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES BASF Aktiengesellschaft (DE) 1985-03-06 EP disclosed
EP-0121129-A1 2,5-Dihydro-5-arylimino-pyrroles, process for their production and their uses as herbicides BASF Aktiengesellschaft (DE) 1984-10-10 EP disclosed
EP-0115808-A1 Cyclohexan-1,3-dione derivatives, process for their preparation and their use as herbicides BASF Aktiengesellschaft (DE) 1984-08-15 EP disclosed
EP-0104389-A2 Quinoline derivatives, process for their preparation and their use in the control of undesired plant growth BASF Aktiengesellschaft (DE) 1984-04-04 EP disclosed
US-4363651-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1982-12-14 US disclosed
EP-0049398-A1 4H-3,1-Benzoxazin derivatives, process for their preparation and their use as herbicides BASF Aktiengesellschaft (DE) 1982-04-14 EP disclosed