⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4990386 | 0.82 | — | — | |
| SCHEMBL7977298 | 0.75 | TSHR (0.41) | — | |
| SCHEMBL16468814 | 0.71 | — | — | |
| SCHEMBL38322 | 0.71 | — | — | |
| SCHEMBL5933072 | 0.69 | — | — | |
| SCHEMBL6545927 | 0.69 | — | — | |
| SCHEMBL1766603 | 0.69 | — | — | |
| Ammonia Solution, Strong SCHEMBL9309545 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL20995323 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL28967109 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 988 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790720-B2 | Compounds comprising an oxazole or thiazole moiety, processes for making them, and their uses | UCB PHARMA, S.A. (BE) | 2010-09-07 | — | — | US | claimed |
| US-20080275046-A1 | Compounds Comprising an Oxazole or Thiazole Moiety, Processes for Making Them, and Their Uses | UCB PHARMA, S.A. (BE) | 2008-11-06 | — | — | US | claimed |
| EP-1866293-A1 | COMPOUNDS COMPRISING AN OXAZOLE OR THIAZOLE MOIETY, PROCESSES FOR MAKING THEM, AND THEIR USES | UCB Pharma, S.A. (BE) | 2007-12-19 | — | — | EP | claimed |
| WO-2006103045-A1 | COMPOUNDS COMPRISING AN OXAZOLE OR THIAZOLE MOIETY, PROCESSES FOR MAKING THEM, AND THEIR USES | UCB PHARMA S.A. (BE) | 2006-10-05 | — | — | WO | claimed |
| EP-0998451-B1 | SUBSTITUTED 3,3-DIAMINO-2-PROPENENITRILES, THEIR PREPARATION AND USE | NOVO NORDISK AS (DK) | 2003-04-16 | — | — | EP | claimed |
| CN-1259119-A | Substituted 3, 3-diamino-2-propenenitriles, their preparation and use | NOVO NORDISK AS (DK) | 2000-07-05 | — | — | CN | claimed |
| EP-0635508-B1 | TETRAHYDROPYRIDINE DERIVATIVE HAVING SUBSTITUENTS ON THREE RINGS | ASAHI CHEMICAL IND (JP) | 1999-10-06 | — | — | EP | claimed |
| EP-0582790-B1 | Novel method of producing 7-(substituted)-9-[(substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines | AMERICAN CYANAMID CO (US) | 1998-12-23 | — | — | EP | claimed |
| EP-0570746-B1 | Thermoplastic moulding mass based on bitumen | BASF AG (DE) | 1997-12-29 | — | — | EP | claimed |
| EP-0635508-A1 | TETRAHYDROPYRIDINE DERIVATIVE HAVING SUBSTITUENTS ON THREE RINGS | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1995-01-25 | — | — | EP | claimed |
| EP-0412907-B1 | New organic acid esters of alcoholic derivatives of 19-nor steroids and their salts, process for their preparation and intermediates thereof, their use as medicines and pharmaceutical compositions containing them | ROUSSEL UCLAF (FR) | 1994-11-09 | — | — | EP | claimed |
| US-5081107-A | Bombesin or bombesin-like peptides antagonists; anticarcinogenic agents; antisecretory agents; glandular disorders | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-14 | — | — | US | claimed |
| US-5068222-A | Polypeptides for treatment of cancer | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-11-26 | — | — | US | claimed |
| EP-0345990-A2 | Polypeptide compounds | ZENECA LIMITED (GB) | 1989-12-13 | — | — | EP | claimed |
| EP-0315367-A2 | Polypeptides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-05-10 | — | — | EP | claimed |
| US-4341551-A | HERBICIDES, FUNGICIDES, PLANT GROWTH REGULATORS | SCHERING AG (DE) | 1982-07-27 | — | — | US | claimed |
| CN-115916777-B | ATX inhibitor and preparation method and application thereof | 苏州爱科百发生物医药技术有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-112912139-B | Biaryl derivatives | 第一三共株式会社 | 2024-07-09 | — | — | CN | disclosed |
| EP-0110434-B1 | STEROID INTERMEDIATES SUBSTITUTED AT POSITION 11, AND PROCESS FOR THEIR PREPARATION | ROUSSEL-UCLAF (FR) | 1986-10-29 | — | — | EP | disclosed |
| EP-0186977-A2 | Renin-inhibitory dipeptides, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1986-07-09 | — | — | EP | disclosed |