SCHEMBL10345129

SCHEMBL10345129

CCCCCc1c(N)c(CCCCC)c(CCCCC)c(N)c1CCCCC

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 2/20 0.41
TLR7 Q9NYK1 1/20 0.41
ALDH1A1 P00352 2/20 0.40
HTR2A P28223 1/20 0.39
TSHR P16473 2/20 0.39
THRB P10828 1/20 0.39
MAPT P10636 1/20 0.39
TYMP P19971 3/20 0.38
DNM1 Q05193 3/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10345217 0.97 TSHR (0.44) TLR8TLR7ALDH1A1HTR2ATSHR
SCHEMBL10345139 0.97 TSHR (0.44) TLR8TLR7ALDH1A1HTR2ATSHR
SCHEMBL10345132 0.97 TSHR (0.44) TLR8TLR7ALDH1A1HTR2ATSHR
SCHEMBL10344837 0.97 TSHR (0.44) TLR8TLR7ALDH1A1HTR2ATSHR
SCHEMBL3695485 0.97 TSHR (0.44) TLR8TLR7ALDH1A1HTR2ATSHR
SCHEMBL29037512 0.94 TLR8 (0.41) TLR8TLR7ALDH1A1HTR2ATSHR
SCHEMBL28466063 0.92 TLR8 (0.40) TLR8TLR7ALDH1A1HTR2ATSHR
SCHEMBL5185158 0.91 SKP2 (0.41) TLR8TLR7ALDH1A1TSHRTHRB
SCHEMBL28748789 0.89 TSHR (0.42) TLR8TLR7ALDH1A1HTR2ATSHR
SCHEMBL9147078 0.89 TSHR (0.42) TLR8TLR7ALDH1A1HTR2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109715765-B Amine salts of alkyl phosphates for use in lubricants 路博润公司 2022-09-30 CN disclosed
US-11384308-B2 Alkyl phosphate amine salts for use in lubricants THE LUBRIZOL CORPORATION (US) 2022-07-12 US disclosed
CN-109715766-B Alkyl phosphate amine salts for use in lubricants 路博润公司 2022-06-28 CN disclosed
EP-3487965-B1 ALKYL PHOSPHATE AMINE SALTS FOR USE IN LUBRICANTS LUBRIZOL CORP (US) 2022-02-09 EP disclosed
US-11168278-B2 Alkyl phosphate amine salts for use in lubricants THE LUBRIZOL CORPORATION (US) 2021-11-09 US disclosed
US-20190241824-A1 ALKYL PHOSPHATE AMINE SALTS FOR USE IN LUBRICANTS THE LUBRIZOL CORPORATION (US) 2019-08-08 US disclosed
US-20190241825-A1 ALKYL PHOSPHATE AMINE SALTS FOR USE IN LUBRICANTS THE LUBRIZOL CORPORATION (US) 2019-08-08 US disclosed
US-9809706-B2 Racemic drug resolution using polymer supported chiral selector COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2017-11-07 US disclosed
US-20160208088-A1 Racemic Drug Resolution Using Polymer Supported Chiral Selector COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2016-07-21 US disclosed
WO-2015029072-A2 RACEMIC DRUG RESOLUTION USING POLYMER SUPPORTED CHIRAL SELECTOR COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2015-03-05 WO disclosed
EP-0365855-A1 Orientation layer composition for liquid crystal display devices Hitachi Chemical Co., Ltd. (JP) 1990-05-02 EP disclosed