Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11862430 | 0.90 | MEN1 (0.63) | MEN1KMT2ATDP1ALDH1A1GLA | |
| SCHEMBL7519513 | 0.88 | MEN1 (0.58) | MEN1KMT2ATDP1ALDH1A1GLA | |
| SCHEMBL27926923 | 0.88 | MEN1 (0.58) | MEN1KMT2ATDP1ALDH1A1GLA | |
| SCHEMBL2549889 | 0.88 | MEN1 (0.58) | MEN1KMT2ATDP1ALDH1A1GLA | |
| SCHEMBL7772965 | 0.85 | MEN1 (0.51) | MEN1KMT2ATDP1ALDH1A1GLA | |
| SCHEMBL11507348 | 0.82 | TAAR1 (0.45) | MEN1KMT2AALDH1A1TSHRSMN1; SMN2 | |
| Butylbenzyl SCHEMBL332884 | 0.82 | MEN1 (0.56) | MEN1KMT2ATDP1ALDH1A1GLA | |
| SCHEMBL8857521 | 0.81 | MEN1 (0.73) | MEN1KMT2ATDP1ALDH1A1MGLL | |
| Ethylbenzene SCHEMBL3241973 | 0.81 | TP53 (0.52) | MEN1KMT2ATDP1ALDH1A1GLA | |
| SCHEMBL332938 | 0.81 | MEN1 (0.55) | MEN1KMT2ATDP1ALDH1A1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0193228-B1 | PROCESS FOR PRODUCING OF 4-(2-METHOXYETHYL)-PHENYLGLYCIDYL ETHER AND/OR METOPROLOL | GIST-BROCADES N.V. (NL) | 1989-11-02 | — | — | EP | claimed |
| CN-86100965-A | Produce 4-(2-methoxyethyl)-phenylglycidyl ether and (or) method of metoprolol | — | 1986-10-01 | — | — | CN | claimed |
| EP-0193228-A1 | Process for producing of 4-(2-methoxyethyl)-phenylglycidyl ether and/or metoprolol | GIST-BROCADES N.V. (NL) | 1986-09-03 | — | — | EP | claimed |
| JP-61254194-A | — | — | None | — | — | JP | disclosed |
| US-4956284-A | Process for producing 4-(2-methoxyethyl)-phenyl-glycidyl ether and/or metoprolol | GIST-BROCADES N.V. (NL) | 1990-09-11 | — | — | US | disclosed |
| EP-0193227-B1 | PROCESS FOR THE PREPARATION OF ARYLGLYCIDYL ETHERS AND 3-SUBSTITUTED 1-ALKYLAMINO-2-PROPANOLS | GIST-BROCADES N.V. (NL) | 1990-04-11 | — | — | EP | disclosed |
| EP-0193228-B1 | PROCESS FOR PRODUCING OF 4-(2-METHOXYETHYL)-PHENYLGLYCIDYL ETHER AND/OR METOPROLOL | GIST-BROCADES N.V. (NL) | 1989-11-02 | — | — | EP | disclosed |
| EP-0193228-B1 | PROCESS FOR PRODUCING OF 4-(2-METHOXYETHYL)-PHENYLGLYCIDYL ETHER AND/OR METOPROLOL | GIST-BROCADES N.V. (NL) | 1989-11-02 | — | — | EP | disclosed |
| CN-86102227-A | The preparation method of 1-alkylamino-2-propyl alcohol that arylolycidyl ethers and 3-replace | — | 1987-02-04 | — | — | CN | disclosed |
| JP-S61254194-A | PRODUCTION OF 4-(2-METHOXYETHYL)-PHENYLGLYCIDYL ETHER AND/ORMETHOPRROLOLE | GIST BROCADES NV | 1986-11-11 | — | — | JP | disclosed |
| CN-86100965-A | Produce 4-(2-methoxyethyl)-phenylglycidyl ether and (or) method of metoprolol | — | 1986-10-01 | — | — | CN | disclosed |
| CN-86100965-A | Produce 4-(2-methoxyethyl)-phenylglycidyl ether and (or) method of metoprolol | — | 1986-10-01 | — | — | CN | disclosed |
| CN-86100965-A | Produce 4-(2-methoxyethyl)-phenylglycidyl ether and (or) method of metoprolol | — | 1986-10-01 | — | — | CN | disclosed |
| EP-0193227-A1 | Process for the preparation of arylglycidyl ethers and 3-substituted 1-alkylamino-2-propanols | GIST-BROCADES N.V. (NL) | 1986-09-03 | — | — | EP | disclosed |
| EP-0193228-A1 | Process for producing of 4-(2-methoxyethyl)-phenylglycidyl ether and/or metoprolol | GIST-BROCADES N.V. (NL) | 1986-09-03 | — | — | EP | disclosed |
| EP-0193228-A1 | Process for producing of 4-(2-methoxyethyl)-phenylglycidyl ether and/or metoprolol | GIST-BROCADES N.V. (NL) | 1986-09-03 | — | — | EP | disclosed |
| EP-0193228-A1 | Process for producing of 4-(2-methoxyethyl)-phenylglycidyl ether and/or metoprolol | GIST-BROCADES N.V. (NL) | 1986-09-03 | — | — | EP | disclosed |