Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 4/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 3/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | FABP4 | P15090 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850727 | 1.00 | EP300 (0.47) | EP300TSHRFAAHTRPV1TERT | |
| SCHEMBL9850729 | 1.00 | EP300 (0.47) | EP300TSHRFAAHTRPV1TERT | |
| SCHEMBL10599906 | 0.98 | EP300 (0.44) | EP300TSHRFAAHTRPV1TERT | |
| SCHEMBL10599903 | 0.98 | EP300 (0.44) | EP300TSHRFAAHTRPV1TERT | |
| SCHEMBL28141100 | 0.75 | TSHR (0.50) | EP300TSHRFAAHTRPV1CYP1A2 | |
| SCHEMBL28141079 | 0.75 | TSHR (0.50) | EP300TSHRFAAHTRPV1CYP1A2 | |
| SCHEMBL14374024 | 0.74 | TSHR (0.54) | EP300TSHRFAAHTRPV1TERT | |
| SCHEMBL1129943 | 0.72 | TSHR (0.52) | EP300TSHRFAAHTRPV1TERT | |
| SCHEMBL1129285 | 0.72 | TSHR (0.52) | EP300TSHRFAAHTRPV1TERT | |
| SCHEMBL1785247 | 0.72 | TSHR (0.52) | EP300TSHRFAAHTRPV1TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0191860-B1 | LIQUID CRYSTAL COMPOUND | SEIKO INSTRUMENTS INC. (JP) | 1990-04-18 | — | — | EP | disclosed |
| US-4725688-A | PHENYLPYRIMIDINE DERIVATIVES; FERROELECTRIC SMECTIC HIGH-SPEED RESPONSE OVER BROAD TEMPERATURE RANGE | SEIKO INSTRUMENTS INC. (JP) | 1988-02-16 | — | — | US | disclosed |
| EP-0191860-A1 | LIQUID CRYSTAL COMPOUND | SEIKO INSTRUMENTS INC. (JP) | 1986-08-27 | — | — | EP | disclosed |