Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.51 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 6/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10346560 | 0.92 | RARB (0.54) | RARBNR5A1TP53TSHRNFKB1 | |
| SCHEMBL10346222 | 0.92 | RARB (0.54) | RARBNR5A1TP53TSHRNFKB1 | |
| SCHEMBL10346180 | 0.92 | RARB (0.54) | RARBNR5A1TP53TSHRNFKB1 | |
| SCHEMBL10346176 | 0.92 | RARB (0.54) | RARBNR5A1TP53TSHRNFKB1 | |
| SCHEMBL10346543 | 0.92 | RARB (0.54) | RARBNR5A1TP53TSHRNFKB1 | |
| SCHEMBL10346241 | 0.92 | RARB (0.54) | RARBNR5A1TP53TSHRNFKB1 | |
| SCHEMBL10346613 | 0.92 | RARB (0.54) | RARBNR5A1TP53TSHRNFKB1 | |
| SCHEMBL10346371 | 0.92 | RARB (0.54) | RARBNR5A1TP53TSHRNFKB1 | |
| SCHEMBL10346612 | 0.84 | RARB (0.57) | RARBNR5A1TP53TSHRNFKB1 | |
| SCHEMBL9343931 | 0.84 | RARB (0.57) | RARBNR5A1TP53TSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0370081-A1 | CHIRAL OR ACHIRAL CYCLIC COMPOUNDS | MERCK PATENT GmbH (DE) | 1990-05-30 | — | — | EP | disclosed |
| WO-1989009764-A1 | CHIRAL OR ACHIRAL CYCLIC COMPOUNDS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-10-19 | — | — | WO | disclosed |