Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7605677 | 1.00 | MEN1 (0.32) | MEN1KMT2AESR1 | |
| SCHEMBL10657556 | 1.00 | MEN1 (0.32) | MEN1KMT2AESR1 | |
| SCHEMBL7441884 | 0.82 | — | — | |
| SCHEMBL3336728 | 0.77 | — | — | |
| SCHEMBL9201057 | 0.69 | — | — | |
| SCHEMBL760162 | 0.67 | POLB (0.39) | — | |
| SCHEMBL4696518 | 0.67 | — | — | |
| SCHEMBL3332425 | 0.67 | — | — | |
| SCHEMBL760161 | 0.67 | POLB (0.39) | — | |
| SCHEMBL2540013 | 0.67 | POLB (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171159-B1 | SUBSTITUTED AZETIDINONE COMPOUNDS, THEIR PREPARATION, AND MEDICAMENTS CONTAINING THEM | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1990-05-30 | — | — | EP | disclosed |
| US-4719207-A | CENTRAL NERVOUS SYSTEM | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1988-01-12 | — | — | US | disclosed |
| EP-0171159-A1 | Substituted azetidinone compounds, their preparation, and medicaments containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1986-02-12 | — | — | EP | disclosed |