Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | BCL9 | O00512 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 2/20 | 0.32 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10347402 | 1.00 | KMT2A (0.36) | KMT2ARAB9ABCL9CTNNB1CYP19A1 | |
| SCHEMBL10347400 | 1.00 | KMT2A (0.36) | KMT2ARAB9ABCL9CTNNB1CYP19A1 | |
| SCHEMBL10347314 | 0.97 | BCL9 (0.39) | KMT2ARAB9ABCL9CTNNB1CYP19A1 | |
| SCHEMBL10347315 | 0.97 | BCL9 (0.39) | KMT2ARAB9ABCL9CTNNB1CYP19A1 | |
| SCHEMBL10347544 | 0.94 | KMT2A (0.37) | KMT2ARAB9ABCL9CTNNB1HCRTR1 | |
| SCHEMBL10347541 | 0.94 | KMT2A (0.37) | KMT2ARAB9ABCL9CTNNB1HCRTR1 | |
| SCHEMBL10347542 | 0.94 | KMT2A (0.37) | KMT2ARAB9ABCL9CTNNB1HCRTR1 | |
| SCHEMBL10347308 | 0.94 | KMT2A (0.35) | KMT2ACYP19A1HCRTR1HCRTR2ACACB | |
| SCHEMBL10347309 | 0.94 | KMT2A (0.35) | KMT2ACYP19A1HCRTR1HCRTR2ACACB | |
| SCHEMBL10347306 | 0.94 | KMT2A (0.35) | KMT2ACYP19A1HCRTR1HCRTR2ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365641-A1 | PYRIDINE DERIVATIVES | MERCK PATENT GmbH (DE) | 1990-05-02 | — | — | EP | disclosed |
| WO-1989010356-A1 | PYRIDINE DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-11-02 | — | — | WO | disclosed |