Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10347413 | 1.00 | KMT2A (0.38) | KMT2ASMN1; SMN2MAPTMEN1ALDH1A1 | |
| SCHEMBL10347270 | 0.97 | KMT2A (0.42) | KMT2ASMN1; SMN2MAPTMEN1ALDH1A1 | |
| SCHEMBL10347269 | 0.97 | KMT2A (0.42) | KMT2ASMN1; SMN2MAPTMEN1ALDH1A1 | |
| SCHEMBL10347358 | 0.95 | KMT2A (0.35) | KMT2ASMN1; SMN2MAPTMEN1ALDH1A1 | |
| SCHEMBL10347360 | 0.94 | KMT2A (0.37) | KMT2ASMN1; SMN2MAPTMEN1ALDH1A1 | |
| SCHEMBL10347359 | 0.94 | KMT2A (0.37) | KMT2ASMN1; SMN2MAPTMEN1ALDH1A1 | |
| SCHEMBL10347580 | 0.93 | KMT2A (0.39) | KMT2ASMN1; SMN2MAPTMEN1ALDH1A1 | |
| SCHEMBL10347329 | 0.93 | BCL9 (0.39) | KMT2AMAPTALDH1A1HPGDKDM4E | |
| SCHEMBL10347327 | 0.93 | BCL9 (0.39) | KMT2AMAPTALDH1A1HPGDKDM4E | |
| SCHEMBL10347161 | 0.92 | KMT2A (0.42) | KMT2ASMN1; SMN2MAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365641-A1 | PYRIDINE DERIVATIVES | MERCK PATENT GmbH (DE) | 1990-05-02 | — | — | EP | disclosed |
| WO-1989010356-A1 | PYRIDINE DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-11-02 | — | — | WO | disclosed |