Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.38 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
| ▸ | TLR4 | O00206 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10531997 | 1.00 | MEN1 (0.49) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL10532002 | 1.00 | MEN1 (0.49) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL10348559 | 1.00 | MEN1 (0.49) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL17225171 | 0.96 | MEN1 (0.46) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL3791147 | 0.96 | MEN1 (0.52) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL1457321 | 0.96 | MEN1 (0.52) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL10348069 | 0.94 | MEN1 (0.51) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL10347915 | 0.92 | MEN1 (0.41) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL10348631 | 0.92 | MEN1 (0.41) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL10417322 | 0.92 | MEN1 (0.49) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3470496-A1 | SPECTACLES WITH REMOTELY ACTIVATABLE DARKENING | Lapanik, Valeri I. (BY) | 2019-04-17 | — | — | EP | disclosed |
| EP-3470496-A1 | SPECTACLES WITH REMOTELY ACTIVATABLE DARKENING | Lapanik, Valeri I. (BY) | 2019-04-17 | — | — | EP | disclosed |
| US-4970022-A | ISOTHIOCYANATES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-11-13 | — | — | US | disclosed |
| EP-0250505-B1 | LIQUID CRYSTAL ISOTHIOCYANATE DERIVATIVES | MERCK PATENT GmbH (DE) | 1990-07-04 | — | — | EP | disclosed |
| US-4877547-A | Liquid crystal display element | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-10-31 | — | — | US | disclosed |
| EP-0258346-A1 | LIQUID CRYSTAL DISPLAY ELEMENT. | MERCK PATENT GMBH (DE) | 1988-03-09 | — | — | EP | disclosed |
| WO-1987005317-A1 | LIQUID CRYSTAL DISPLAY ELEMENT | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1987-09-11 | — | — | WO | disclosed |