Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | CASP1 | P29466 | 1/20 | 0.70 |
| ▸ | CASP7 | P55210 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | MITF | O75030 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.64 |
| ▸ | PLG | P00747 | 2/20 | 0.55 |
| ▸ | KLK1 | P06870 | 2/20 | 0.55 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL10349263 | 0.98 | MAPT (0.68) | MAPTKDM4EALDH1A1CASP1CASP7 | |
| Hydrochloric Acid SCHEMBL10348724 | 0.98 | MAPT (0.68) | MAPTKDM4EALDH1A1CASP1CASP7 | |
| Hydrochloric Acid SCHEMBL10349260 | 0.94 | KDM4E (0.67) | MAPTKDM4EALDH1A1CASP1CASP7 | |
| SCHEMBL11568743 | 0.91 | MAPT (0.74) | MAPTKDM4EALDH1A1CASP1CASP7 | |
| SCHEMBL10819824 | 0.90 | KDM4E (0.62) | MAPTKDM4EALDH1A1CASP1CASP7 | |
| Hydrochloric Acid SCHEMBL10348698 | 0.89 | MAPT (0.72) | MAPTKDM4EALDH1A1CASP1CASP7 | |
| SCHEMBL11439147 | 0.87 | MAPT (0.84) | MAPTKDM4EALDH1A1CASP1CASP7 | |
| SCHEMBL11333817 | 0.86 | MAPT (0.82) | MAPTKDM4EALDH1A1CASP1CASP7 | |
| SCHEMBL10819816 | 0.86 | KDM4E (0.56) | MAPTKDM4EALDH1A1CASP1CASP7 | |
| SCHEMBL10423855 | 0.84 | MAPT (0.68) | MAPTKDM4EALDH1A1CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0141377-B1 | METAL COMPLEXES | HODOGAYA CHEMICAL CO., LTD. (JP) | 1990-05-02 | — | — | EP | disclosed |