SCHEMBL1034893

SCHEMBL1034893

CN1[CH]C=CC=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9673094 0.81
SCHEMBL23234265 0.81 MEN1 (0.41)
SCHEMBL27694695 0.71 MEN1 (0.35)
Butane SCHEMBL27616613 0.69 MEN1 (0.33)
SCHEMBL10017669 0.61
SCHEMBL4216460 0.59
SCHEMBL11255228 0.57
SCHEMBL15789299 0.57
SCHEMBL1752289 0.57
SCHEMBL11843672 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 524 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113979887-A Synthetic method of aromatic amine carboxylic acid derivative 北京亦农生物科技有限公司 2022-01-28 CN claimed
US-8344102-B2 Nanoparticle and magnetic resonance imaging contrast agent NATIONAL CHIAO TUNG UNIVERSITY (TW) 2013-01-01 US claimed
EP-1806586-B1 Mass labels ELECTROPHORETICS LTD (GB) 2012-08-15 EP claimed
US-20110092672-A1 NANOPARTICLE AND MAGNETIC RESONANCE IMAGING CONTRAST AGENT NATIONAL CHIAO TUNG UNIVERSITY (TW) 2011-04-21 US claimed
US-7879852-B2 such as (4S)-1-{[(3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidine-3-yl]carbonyl}-4-[(4,4-dimethylcyclohexyl)(2,2-dimethylpropanoyl)amino]-N,N-dimethyl-L-prolineamide, used for the treatment of obesity, diabetes, inflammation and erectile dysfunction LG LIFE SCIENCES LTD. (KR) 2011-02-01 US claimed
US-20090298829-A1 MELANOCORTIN RECEPTOR AGONISTS LG LIFE SCIENCES LTD. (KR) 2009-12-03 US claimed
EP-2124946-A1 THE USE OF QUATERNARY PYRIDINIUM COMPOUNDS FOR VASOPROTECTION AND/OR HEPATOPROTECTION Trigendo Sp. Z O.o. (PL) 2009-12-02 EP claimed
WO-2008007930-A9 MELANOCORTIN RECEPTOR AGONISTS LG LIFE SCIENCES LTD (KR) 2009-04-02 WO claimed
EP-2041120-A1 MELANOCORTIN RECEPTOR AGONISTS LG Life Sciences Ltd. (KR) 2009-04-01 EP claimed
WO-2008104920-A1 THE USE OF QUATERNARY PYRIDINIUM COMPOUNDS FOR VASOPROTECTION AND/OR HEPATOPROTECTION TRIGENDO SP. Z O.O. (PL) 2008-09-04 WO claimed
EP-0645379-B1 Benzoylacetylene derivatives MITSUBISHI CHEM CORP (JP) 1999-03-17 EP claimed
WO-1999006434-A1 4-AMINO-PHENYLALANINE TYPE COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 ELAN PHARMACEUTICALS INC. (US) 1999-02-11 WO claimed
WO-1999006433-A1 COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 ELAN PHARMACEUTICALS, INC. (US) 1999-02-11 WO claimed
WO-1999006435-A1 DIPEPTIDE COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 ELAN PHARMACEUTICALS, INC. (US) 1999-02-11 WO claimed
WO-1999006390-A1 CARBAMYLOXY COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 ELAN PHARMACEUTICALS, INC. (US) 1999-02-11 WO claimed
EP-0645379-A2 Benzoylacetylene derivatives Mitsubishi Chemical Corporation (JP) 1995-03-29 EP claimed
EP-0189287-B1 NOVEL B-LACTAM ANTIBIOTICS NIPPON PHARMACEUTICAL DEVELOPMENT INSTITUTE COMPANY LIMITED (JP) 1992-12-16 EP claimed
WO-1992003732-A2 COMPOSITIONS AND METHODS FOR ENHANCED BINDING IN BIOLOGICAL ASSAYS BIOPROBE INTERNATIONAL, INC. (US) 1992-03-05 WO claimed
US-4808711-A EFFECTIVE AGAINST PSEUDOMONAS AERUGINOSA SANKEI PHARMACEUTICAL CO., LTD. (JP) 1989-02-28 US claimed
EP-0189287-A2 Novel B-lactam antibiotics NIPPON PHARMACEUTICAL DEVELOPMENT INSTITUTE COMPANY LIMITED (JP) 1986-07-30 EP claimed