Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | PRKCG | P05129 | 1/20 | 0.34 |
| ▸ | PRKCB | P05771 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | PRKCH | P24723 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1318572 | 0.80 | USP2 (0.52) | USP2TSHRSPHK1HTTCYP3A4 | |
| SCHEMBL1318570 | 0.80 | USP2 (0.38) | USP2TSHRSPHK1HTTCYP3A4 | |
| SCHEMBL6933501 | 0.77 | — | — | |
| SCHEMBL11883676 | 0.76 | LPAR1 (0.46) | USP2TSHRHTTCYP3A4PRKD3 | |
| SCHEMBL8958246 | 0.76 | USP2 (0.57) | USP2TSHRSPHK1HTTCYP3A4 | |
| SCHEMBL9121906 | 0.75 | — | — | |
| SCHEMBL10519445 | 0.75 | SPHK1 (0.39) | USP2TSHRSPHK1HTTCYP3A4 | |
| Chloroform SCHEMBL28238708 | 0.75 | TSHR (0.57) | USP2TSHRHTTCYP3A4SMN1; SMN2 | |
| SCHEMBL27199988 | 0.74 | — | — | |
| SCHEMBL1627599 | 0.74 | TP53 (0.42) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4841081-A | Method of optically resolving a racemate or a diastereomeric mixture of glycidyl compound | OSAKA SODA CO., LTD. (JP) | 1989-06-20 | — | — | US | claimed |
| EP-0220887-B1 | METHOD OF OPTICALLY RESOLVING A RACEMATE OR A DIASTEREOMERIC MIXTURE OF GLYCIDYL COMPOUND | Daiso Co., Ltd. (JP) | 1990-06-27 | — | — | EP | disclosed |
| EP-0220887-A1 | Method of optically resolving a racemate or a diastereomeric mixture of glycidyl compound | Daiso Co., Ltd. (JP) | 1987-05-06 | — | — | EP | disclosed |