Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | BCL3 | P20749 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10352662 | 0.92 | KMT2A (0.65) | ALDH1A1BCL3HPGDGAAKMT2A | |
| SCHEMBL10352502 | 0.88 | POLB (0.50) | POLBALDH1A1KDM4ESMN1; SMN2BCL3 | |
| SCHEMBL10652624 | 0.87 | NAMPT (0.50) | POLBTSHR | |
| SCHEMBL2362567 | 0.84 | POLB (0.66) | POLBALDH1A1KDM4ESMN1; SMN2BCL3 | |
| SCHEMBL7526242 | 0.84 | POLB (0.66) | POLBALDH1A1KDM4ESMN1; SMN2BCL3 | |
| SCHEMBL12333386 | 0.82 | POLB (0.65) | POLBALDH1A1KDM4ESMN1; SMN2BCL3 | |
| SCHEMBL12305552 | 0.81 | POLB (0.62) | POLBALDH1A1KDM4ESMN1; SMN2BCL3 | |
| SCHEMBL1382764 | 0.80 | SMN1; SMN2 (0.95) | POLBALDH1A1KDM4ESMN1; SMN2TSHR | |
| SCHEMBL13385672 | 0.80 | POLB (0.61) | POLBALDH1A1KDM4ESMN1; SMN2BCL3 | |
| SCHEMBL14525845 | 0.80 | POLB (0.71) | POLBALDH1A1KDM4ESMN1; SMN2BCL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257306-B1 | DISELENOBIS BENZOIC ACID AMIDES OF PRIMARY HETEROCYCLIC AMINES, PROCESS FOR PRODUCING THE SAME AND PHARMACEUTICAL COMPOUNDS COMPRISING THE SAME | A. Nattermann & Cie. GmbH (DE) | 1990-09-12 | — | — | EP | disclosed |
| EP-0257306-A1 | Diselenobis benzoic acid amides of primary heterocyclic amines, process for producing the same and pharmaceutical compounds comprising the same | A. Nattermann & Cie. GmbH (DE) | 1988-03-02 | — | — | EP | disclosed |