SCHEMBL10353571

SCHEMBL10353571

c1ccc2c(c1)c1ccccc1n2-c1ccc2[nH]c3ccc(-c4ccc5[nH]c6ccc(-n7c8ccccc8c8ccccc87)cc6c5c4)cc3c2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.46
ATM Q13315 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
AHR P35869 2/20 0.41
ALDH1A1 P00352 3/20 0.38
HSD17B10 Q99714 2/20 0.38
GPR3 P46089 1/20 0.38
KIF11 P52732 6/20 0.37
HPGD P15428 3/20 0.37
MEN1 O00255 1/20 0.37
MAPT P10636 1/20 0.37
KMT2A Q03164 1/20 0.37
TP53 P04637 1/20 0.36
CDK4 P11802 1/20 0.36
CCND1 P24385 1/20 0.36
HDAC4 P56524 1/20 0.35
PTGER4 P35408 1/20 0.34
GAA P10253 2/20 0.34
HTT P42858 2/20 0.34
EDNRB P24530 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22514649 0.95 KDM4E (0.46) KDM4EATML3MBTL1AHRKIF11
SCHEMBL22137212 0.95 KDM4E (0.42) KDM4EATML3MBTL1AHRALDH1A1
SCHEMBL21583634 0.94 KDM4E (0.44) KDM4EATML3MBTL1AHRALDH1A1
SCHEMBL261158 0.93 KDM4E (0.50) KDM4EATML3MBTL1AHRALDH1A1
SCHEMBL45708 0.93 KDM4E (0.52) KDM4EATML3MBTL1AHRALDH1A1
SCHEMBL29354460 0.93 KDM4E (0.52) KDM4EATML3MBTL1AHRALDH1A1
SCHEMBL25106493 0.93 KDM4E (0.43) KDM4EATML3MBTL1AHRKIF11
SCHEMBL12076840 0.93 KDM4E (0.43) KDM4EATML3MBTL1AHRKIF11
SCHEMBL24667952 0.93 KDM4E (0.43) KDM4EATML3MBTL1AHRKIF11
SCHEMBL18058370 0.93 KDM4E (0.43) KDM4EATML3MBTL1AHRKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9780322-B2 Organic electroluminescent element Konica Minolta, Inc. (JP) 2017-10-03 US disclosed
EP-2463930-B1 Organic electroluminescent device, display and illuminating device KONICA MINOLTA HOLDINGS INC (JP) 2017-04-12 EP disclosed
US-8221908-B2 Organic electroluminescent device, display, and illuminating device KONICA MINOLTA HOLDINGS, INC. (JP) 2012-07-17 US disclosed
US-20110168990-A1 ORGANIC ELECTROLUMINESCENT DEVICE, DISPLAY, AND ILLUMINATING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2011-07-14 US disclosed
US-7935434-B2 Organic electroluminescent device, display, and illuminating device KONICA MINOLTA HOLDINGS, INC. (JP) 2011-05-03 US disclosed
US-7935434-B2 Organic electroluminescent device, display, and illuminating device KONICA MINOLTA HOLDINGS, INC. (JP) 2011-05-03 US disclosed
US-20090096360-A1 ORGANIC ELECTROLUMINESCENT DEVICE, DISPLAY, AND ILLUMINATING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2009-04-16 US disclosed
US-20090096360-A1 ORGANIC ELECTROLUMINESCENT DEVICE, DISPLAY, AND ILLUMINATING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2009-04-16 US disclosed
EP-1970976-A1 ORGANIC ELECTROLUMINESCENT DEVICE, DISPLAY AND ILLUMINATING DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2008-09-17 EP disclosed