Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | FAAH | O00519 | 2/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ADH1B | P00325 | 2/20 | 0.45 |
| ▸ | ADH1C | P00326 | 2/20 | 0.45 |
| ▸ | ADH1A | P07327 | 2/20 | 0.45 |
| ▸ | ADH4 | P08319 | 2/20 | 0.45 |
| ▸ | ADH7 | P40394 | 2/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.39 |
| ▸ | GAPDH | P04406 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
| ▸ | FDPS | P14324 | 3/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25907690 | 1.00 | TSHR (0.65) | TSHRFAAHTRPV1LMNAADH1B | |
| SCHEMBL9425832 | 1.00 | TSHR (0.65) | TSHRFAAHTRPV1LMNAADH1B | |
| SCHEMBL9260986 | 0.96 | TSHR (0.60) | TSHRFAAHTRPV1LMNAADH1B | |
| SCHEMBL6862076 | 0.95 | TSHR (0.58) | TSHRFAAHTRPV1LMNAADH1B | |
| SCHEMBL22602593 | 0.95 | TSHR (0.73) | TSHRFAAHTRPV1LMNAADH1B | |
| SCHEMBL17750778 | 0.93 | TSHR (0.56) | TSHRFAAHTRPV1LMNAADH1B | |
| SCHEMBL29109640 | 0.91 | TSHR (0.60) | TSHRFAAHTRPV1LMNAADH1B | |
| SCHEMBL9264608 | 0.91 | TSHR (0.67) | TSHRFAAHTRPV1LMNAADH1B | |
| SCHEMBL19759291 | 0.91 | TSHR (0.58) | TSHRFAAHTRPV1LMNAADH1B | |
| SCHEMBL9257903 | 0.91 | TSHR (0.58) | TSHRFAAHTRPV1LMNAADH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399422-B2 | Compositions for transfection of oligonucleotides active for gene silencing and their biological and therapeutical applications | POLYPLUS-TRANSFECTION (FR) | 2013-03-19 | — | — | US | disclosed |
| US-8399422-B2 | Compositions for transfection of oligonucleotides active for gene silencing and their biological and therapeutical applications | POLYPLUS-TRANSFECTION (FR) | 2013-03-19 | — | — | US | disclosed |
| EP-2004156-B1 | COMPOSITIONS FOR TRANSFECTION OF OLIGONUCLEOTIDES ACTIVE FOR GENE SILENCING AND THEIR BIOLOGICAL AND THERAPEUTICAL APPLICATIONS | POLYPLUS TRANSFECTION SA (FR) | 2011-01-26 | — | — | EP | disclosed |
| US-20100048672-A1 | COMPOSITIONS FOR TRANSFECTION OF OLIGONUCLEOTIDES ACTIVE FOR GENE SILENCING AND THEIR BIOLOGICAL AND THERAPEUTICAL APPLICATIONS | POLYPLUS-TRANSFECTION (FR) | 2010-02-25 | — | — | US | disclosed |
| US-20100048672-A1 | COMPOSITIONS FOR TRANSFECTION OF OLIGONUCLEOTIDES ACTIVE FOR GENE SILENCING AND THEIR BIOLOGICAL AND THERAPEUTICAL APPLICATIONS | POLYPLUS-TRANSFECTION (FR) | 2010-02-25 | — | — | US | disclosed |
| EP-2004156-A2 | COMPOSITIONS FOR TRANSFECTION OF OLIGONUCLEOTIDES ACTIVE FOR GENE SILENCING AND THEIR BIOLOGICAL AND THERAPEUTICAL APPLICATIONS | Polyplus-Transfection SA (FR) | 2008-12-24 | — | — | EP | disclosed |
| WO-2008004058-A2 | COMPOSITIONS FOR TRANSFECTION OF OLIGONUCLEOTIDES ACTIVE FOR GENE SILENCING AND THEIR BIOLOGICAL AND THERAPEUTICAL APPLICATIONS | POLYPLUS-TRANSFECTION SA (FR) | 2008-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048672-A1 | COMPOSITIONS FOR TRANSFECTION OF OLIGONUCLEOTIDES ACTIVE FOR GENE SILENCING AND THEIR BIOLOGICAL AND THERAPEUTICAL APPLICATIONS | C1R, C1S, C3AR1 | TSHR 668/4885FAAH 1120/4885TRPV1 2018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.