Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16187772 | 0.87 | ESR1 (0.39) | MAPTNPC1RAB9ASMN1; SMN2ESR1 | |
| SCHEMBL104020 | 0.86 | MAPT (0.48) | MAPTNPC1RAB9ASMN1; SMN2ESR1 | |
| SCHEMBL13310802 | 0.80 | MAPT (0.53) | MAPTNPC1RAB9ASMN1; SMN2ESR1 | |
| SCHEMBL17754279 | 0.80 | MAPT (0.40) | MAPTNPC1RAB9ASMN1; SMN2ESR1 | |
| SCHEMBL102867 | 0.78 | NPC1 (0.54) | MAPTNPC1RAB9ASMN1; SMN2ESR1 | |
| SCHEMBL103320 | 0.78 | MAPT (0.38) | MAPTNPC1RAB9ASMN1; SMN2ESR1 | |
| SCHEMBL26079332 | 0.78 | MAPT (0.35) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL103172 | 0.78 | ESR1 (0.55) | MAPTNPC1RAB9ASMN1; SMN2ESR1 | |
| SCHEMBL12931954 | 0.77 | MAPT (0.41) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL13310804 | 0.75 | TYR (0.41) | MAPTNPC1RAB9ASMN1; SMN2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8992796-B2 | Polymerizable liquid crystal composition | DIC CORPORATION (JP) | 2015-03-31 | — | — | US | disclosed |
| US-20120056129-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOSITION | DIC CORPORATION (JP) | 2012-03-08 | — | — | US | disclosed |