Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10745086 | 0.90 | MAPT (0.53) | PDE4BHDAC8HDAC1MAPTMEN1 | |
| SCHEMBL10745082 | 0.90 | MAPT (0.53) | PDE4BHDAC8HDAC1MAPTMEN1 | |
| SCHEMBL3383975 | 0.83 | PDE4B (0.55) | PDE4BHDAC8HDAC1MAPTMEN1 | |
| SCHEMBL22034392 | 0.81 | HDAC8 (0.64) | PDE4BHDAC8HDAC1MAPTL3MBTL1 | |
| SCHEMBL12855893 | 0.81 | PDE4B (0.62) | PDE4BHDAC8HDAC1MAPTMEN1 | |
| SCHEMBL3171960 | 0.81 | PDE4B (0.79) | PDE4BHDAC8HDAC1MAPTKMT2A | |
| SCHEMBL7180991 | 0.79 | HDAC8 (0.54) | PDE4BHDAC8HDAC1MAPTMEN1 | |
| SCHEMBL10585461 | 0.79 | STS (0.49) | KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL10585963 | 0.79 | STS (0.49) | KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL3383272 | 0.79 | PDE4B (0.82) | PDE4BHDAC8HDAC1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0256307-B1 | OPTICALLY ACTIVE COMPOUNDS HAVING BIPHENYL SKELETON, LIQUID CRYSTAL COMPOSITION AND SWITCHING ELEMENT CONTAINING THEM | Chisso Corporation (JP) | 1990-10-03 | — | — | EP | disclosed |