Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | FYN | P06241 | 2/20 | 0.45 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.45 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.45 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10355385 | 0.98 | IDO1 (0.48) | IDO1ALDH1A1FYNCCNB2CDK1 | |
| SCHEMBL10355641 | 0.83 | IDO1 (0.42) | IDO1ALDH1A1CCNB2CDK1CCNB1 | |
| Hydrochloric Acid SCHEMBL10355404 | 0.82 | IDO1 (0.41) | IDO1ALDH1A1CCNB2CDK1CCNB1 | |
| SCHEMBL11004015 | 0.78 | DYRK1A (0.47) | IDO1FYNCCNB2CDK1CCNB1 | |
| Hydrochloric Acid SCHEMBL10355432 | 0.77 | DYRK1A (0.46) | IDO1FYNCCNB2CDK1CCNB1 | |
| SCHEMBL27915583 | 0.77 | MAPK14 (0.56) | IDO1FYNCCNB2CDK1CCNB1 | |
| SCHEMBL10355257 | 0.76 | KDM4E (0.39) | IDO1MAPTGAAKDM4E | |
| SCHEMBL10355621 | 0.75 | HPGD (0.56) | ALDH1A1PDGFRBPDGFRAKMT2AMAPT | |
| SCHEMBL10355357 | 0.74 | IDO1 (0.58) | IDO1ALDH1A1FYNCCNB2CDK1 | |
| SCHEMBL10355322 | 0.74 | CYP11B1 (0.44) | IDO1ALDH1A1KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0074130-B1 | NEW IMIDAZOLE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ZAMBON S.p.A. (IT) | 1990-09-19 | — | — | EP | disclosed |
| US-4560696-A | Analgesic, antipyretic or anti-inflammatory imidazole compounds | ZAMBON S.P.A. (IT) | 1985-12-24 | — | — | US | disclosed |
| EP-0074130-A2 | New imidazole compounds, process for the preparation thereof and pharmaceutical compositions containing them | ZAMBON S.p.A. (IT) | 1983-03-16 | — | — | EP | disclosed |