Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10355466 | 1.00 | MAPT (0.42) | MAPTGAADEGS1MEN1KMT2A | |
| SCHEMBL10460862 | 0.84 | MAPT (0.43) | MAPTGAAMEN1KMT2ANPC1 | |
| SCHEMBL9805447 | 0.84 | GAA (0.43) | MAPTGAAMEN1KMT2ANPC1 | |
| SCHEMBL10460863 | 0.84 | MAPT (0.43) | MAPTGAAMEN1KMT2ANPC1 | |
| SCHEMBL9805435 | 0.84 | GAA (0.43) | MAPTGAAMEN1KMT2ANPC1 | |
| SCHEMBL11082370 | 0.84 | MAPT (0.48) | MAPTGAAMEN1KMT2ANPC1 | |
| SCHEMBL11084354 | 0.84 | MAPT (0.48) | MAPTGAAMEN1KMT2ANPC1 | |
| SCHEMBL11084351 | 0.84 | MAPT (0.48) | MAPTGAAMEN1KMT2ANPC1 | |
| SCHEMBL11082366 | 0.84 | MAPT (0.48) | MAPTGAAMEN1KMT2ANPC1 | |
| SCHEMBL10470975 | 0.83 | GAA (0.41) | MAPTGAAMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194153-B1 | PYRIDINE DERIVATIVES | Chisso Corporation (JP) | 1990-10-31 | — | — | EP | disclosed |
| US-4684477-A | LOW VISCOSITY, LOW VOLTAGE | CHISSO CORPORATION (JP) | 1987-08-04 | — | — | US | disclosed |
| EP-0194153-A2 | Pyridine derivatives | Chisso Corporation (JP) | 1986-09-10 | — | — | EP | disclosed |