Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 18/20 | 0.72 |
| ▸ | SLC5A1 | P13866 | 10/20 | 0.70 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.68 |
| ▸ | SLC5A11 | Q8WWX8 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1666220 | 1.00 | SLC5A2 (0.72) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL1035551 | 1.00 | SLC5A2 (0.72) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL22942125 | 1.00 | SLC5A2 (0.72) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL1035411 | 1.00 | SLC5A2 (0.72) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL14305460 | 0.91 | SLC5A2 (0.65) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL14108336 | 0.89 | SLC5A2 (0.69) | SLC5A2SLC5A1 | |
| SCHEMBL20646294 | 0.89 | SLC5A2 (0.71) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL18685126 | 0.87 | SLC5A2 (0.63) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL22931090 | 0.87 | SLC5A2 (0.63) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL19528502 | 0.87 | SLC5A2 (0.63) | SLC5A2SLC5A1ADRA2ASLC5A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2089361-B1 | INHIBITORS OF SODIUM GLUCOSE CO-TRANSPORTER 2 AND METHODS OF THEIR USE | LEXICON PHARMACEUTICALS INC (US) | 2011-01-26 | — | — | EP | disclosed |