SCHEMBL1035563

SCHEMBL1035563

Cl[Si](Cl)(Cl)C1=CCCCC1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.32
HDAC4 P56524 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28472081 0.97 KDM1A (0.31) KDM1AHDAC4HDAC2HDAC8HDAC6
SCHEMBL28471659 0.97 KDM1A (0.31) KDM1AHDAC4HDAC2HDAC8HDAC6
SCHEMBL28472056 0.97 KDM1A (0.31) KDM1AHDAC4HDAC2HDAC8HDAC6
SCHEMBL4521872 0.92
SCHEMBL299770 0.80 KDM1A (0.30) KDM1A
SCHEMBL4272346 0.80 KDM1A (0.30) KDM1A
SCHEMBL17241764 0.78
SCHEMBL28477298 0.77
SCHEMBL7125955 0.76 KDM1A (0.33) KDM1AHDAC4HDAC2HDAC8HDAC6
SCHEMBL3157330 0.74 KDM1A (0.32) KDM1AHDAC4HDAC2HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105399910-A A styrene-conjugated diene block copolymer and a preparing method thereof UNIV SHENYANG CHEMICAL TECH 2016-03-16 CN claimed
CN-104262515-A Method for preparing granular random/stereoblock polystyrene UNIV SHENYANG CHEMICAL TECH 2015-01-07 CN claimed
CN-103992347-A Epoxy heptaphenyl silsesquioxane material and preparation method thereof UNIV SHANGHAI 2014-08-20 CN claimed
EP-2276793-A1 SULFUR MODIFIED SILANES FOR THE ELABORATION OF HIGH REFRACTIVE INDEX MATERIALS Essilor International (Compagnie Générale d'Optique) (FR) 2011-01-26 EP claimed
WO-2009138853-A1 SULFUR MODIFIED SILANES FOR THE ELABORATION OF HIGH REFRACTIVE INDEX MATERIALS ESSILOR INTERNATIONAL (FR) 2009-11-19 WO claimed
CN-109608205-B Method for preparing equiaxed alpha-phase silicon nitride powder 清华大学 2021-04-16 CN disclosed
CN-106831845-B Boron-containing organosilicon compounds, method for the production and use thereof 北京康美特科技股份有限公司 2021-01-26 CN disclosed
CN-106854451-B Sealing agent for solar cell module, and sealing method for solar cell module 北京康美特科技股份有限公司 2020-10-02 CN disclosed
CN-105399910-A A styrene-conjugated diene block copolymer and a preparing method thereof UNIV SHENYANG CHEMICAL TECH 2016-03-16 CN disclosed
CN-104262515-A Method for preparing granular random/stereoblock polystyrene UNIV SHENYANG CHEMICAL TECH 2015-01-07 CN disclosed
CN-103992347-A Epoxy heptaphenyl silsesquioxane material and preparation method thereof UNIV SHANGHAI 2014-08-20 CN disclosed
CN-101410437-B Curable resin, curable resin compositions and moldings thereof NIPPON STEEL CHEMICAL CO 2012-01-04 CN disclosed
EP-0669347-B1 Ethylene polymer, and process for preparing the same MITSUI PETROCHEMICAL IND (JP) 1998-05-06 EP disclosed
US-5731393-A Ethylene polymer, process for preparing the same, solid titanium catalyst component for ethylene polymerization and ethylene polymerization catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1998-03-24 US disclosed
EP-0821018-A2 Crosslinkable olefinic polymers and method for their preparation PCD-Polymere Gesellschaft m.b.H. (AT) 1998-01-28 EP disclosed
EP-0669347-A1 Ethylene polymer, process for preparing the same, solid titanium catalyst component for ethylene polymerization and ethylene polymerization catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-08-30 EP disclosed
EP-0668296-A1 Ethylene polymer and process for preparing the same MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-08-23 EP disclosed
EP-0115772-B1 PROCESS FOR THE SPLITTING OF ORGANOSILOXANES AND RESULTING PRODUCTS AND THEIR APPLICATIONS HÜLS AKTIENGESELLSCHAFT (DE) 1989-02-15 EP disclosed
EP-0115772-A2 Process for the splitting of organosiloxanes and resulting products and their applications HÜLS AKTIENGESELLSCHAFT (DE) 1984-08-15 EP disclosed
US-4229558-A HAVING HIGH ISOTACTIC INDEX BY USING A CATALYST PREPARED FROM A MAGNESIUM GRIGNARD REAGENT, TITANIUM HALIDE AN ETHER AND A CARBOXYLIC ESTER COMBINED WITH AN ORGANOALUMINUM COMPOUND MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1980-10-21 US disclosed