Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | SMO | Q99835 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12306482 | 0.82 | CCR1 (0.39) | PDK2CCR1CCR5CCR8NOS3 | |
| SCHEMBL26266853 | 0.77 | KMT2A (0.33) | PDK2CCR1CCR5CCR8NOS3 | |
| SCHEMBL10356735 | 0.76 | CCR1 (0.34) | CCR1CCR5CCR8NOS3NOS1 | |
| SCHEMBL27241020 | 0.76 | CYP17A1 (0.41) | PDK2CCR1CCR5CCR8KMT2A | |
| SCHEMBL26267081 | 0.74 | CCR1 (0.35) | PDK2CCR1CCR5CCR8NOS3 | |
| SCHEMBL10356375 | 0.74 | MAPT (0.40) | PDK2KMT2AKDM4EALDH1A1POLB | |
| SCHEMBL10356404 | 0.73 | KDM4E (0.33) | KMT2AKDM4EALDH1A1POLBGAA | |
| SCHEMBL10356671 | 0.73 | UHRF1 (0.38) | NOS3NOS1NOS2ALDH1A1GAA | |
| SCHEMBL10356400 | 0.73 | KDM4E (0.41) | KDM4EALDH1A1POLBGAAMAPT | |
| SCHEMBL25983070 | 0.73 | CYP2A6 (0.40) | PDK2CCR1CCR8NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8378340-B2 | Aromatic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-02-19 | — | — | US | disclosed |
| US-20120238765-A1 | AROMATIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-09-20 | — | — | US | disclosed |
| US-8222426-B2 | Aromatic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-07-17 | — | — | US | disclosed |
| US-7842941-B2 | Aromatic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-11-30 | — | — | US | disclosed |
| US-20100256396-A1 | AROMATIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-10-07 | — | — | US | disclosed |
| US-20070063190-A1 | Aromatic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256396-A1 | AROMATIC COMPOUND | AHR, AR, NR0B1 | PDK2 4575/4885CCR1 544/4885CCR5 1086/4885 |
| US-20070063190-A1 | Aromatic compound | AHR, AR, NR0B1 | PDK2 4573/4885CCR1 610/4885CCR5 1211/4885 |
| US-20120238765-A1 | AROMATIC COMPOUND | AHR, AR, NR0B1 | PDK2 4575/4885CCR1 544/4885CCR5 1086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.