Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 7/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3294827 | 0.84 | KDM4C (0.44) | KDM4CNPC1RAB9AMEN1KMT2A | |
| SCHEMBL12200512 | 0.81 | KDM4C (0.46) | KDM4CNPC1RAB9AMEN1KMT2A | |
| SCHEMBL26982209 | 0.81 | KDM4C (0.49) | KDM4CNPC1RAB9AMEN1KMT2A | |
| SCHEMBL4988791 | 0.77 | NPC1 (0.44) | KDM4CNPC1RAB9AMEN1KMT2A | |
| SCHEMBL15244186 | 0.76 | KDM4C (0.47) | KDM4CNPC1RAB9AMEN1KMT2A | |
| SCHEMBL25918360 | 0.75 | KDM4C (0.49) | KDM4CNPC1RAB9AMEN1KMT2A | |
| SCHEMBL171304 | 0.75 | MEN1 (0.59) | KDM4CNPC1RAB9AMEN1KMT2A | |
| SCHEMBL26036032 | 0.74 | KDM4C (0.46) | KDM4CNPC1RAB9AMEN1KMT2A | |
| SCHEMBL11994822 | 0.74 | KDM4C (0.43) | KDM4CNPC1RAB9AMEN1KMT2A | |
| SCHEMBL17323672 | 0.74 | KMT2A (0.57) | KDM4CNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121600-B1 | SUBSTITUTED ARYLSULPHONYLGLYCINES, THE PREPARATION THEREOF AND THE USE THEREOF AS PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM INT (DE) | 2012-07-18 | — | — | EP | disclosed |