Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1034660 | 0.89 | SLC6A4 (0.72) | SLC6A4HRH3 | |
| SCHEMBL1035381 | 0.89 | SLC6A4 (0.82) | SLC6A4HRH3 | |
| SCHEMBL1035728 | 0.88 | SLC6A4 (0.72) | SLC6A4HRH3 | |
| SCHEMBL1036847 | 0.86 | SLC6A4 (0.75) | SLC6A4HRH3 | |
| SCHEMBL1033191 | 0.86 | SLC6A4 (0.90) | SLC6A4HRH3 | |
| SCHEMBL1036182 | 0.85 | SLC6A4 (1.00) | SLC6A4HRH3 | |
| SCHEMBL1032495 | 0.84 | SLC6A4 (1.00) | SLC6A4HRH3 | |
| SCHEMBL1035573 | 0.84 | SLC6A4 (0.86) | SLC6A4HRH3 | |
| SCHEMBL1038596 | 0.84 | SLC6A4 (0.83) | SLC6A4HRH3 | |
| SCHEMBL1035488 | 0.84 | SLC6A4 (0.82) | SLC6A4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831173-B1 | TETRAHYDROISOQUINOLINE COMPOUNDS FOR TREATMENT OF CNS DISORDERS | JANSSEN PHARMACEUTICA NV (BE) | 2011-01-26 | — | — | EP | claimed |