Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIG1 | P18858 | 1/20 | 0.89 |
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | RAB9A | P51151 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | CDC25B | P30305 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.55 |
| ▸ | STS | P08842 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28952571 | 0.94 | LIG1 (0.79) | LIG1MAPTMEN1KMT2ALMNA | |
| SCHEMBL1568564 | 0.94 | LIG1 (1.00) | LIG1MAPTMEN1KMT2ALMNA | |
| SCHEMBL29512266 | 0.94 | LIG1 (1.00) | LIG1MAPTMEN1KMT2ALMNA | |
| SCHEMBL5380007 | 0.89 | LIG1 (0.89) | LIG1MAPTMEN1KMT2ALMNA | |
| 2,2'-Dihydroxybenzphenone SCHEMBL20578587 | 0.88 | LIG1 (0.88) | LIG1MAPTMEN1KMT2ALMNA | |
| SCHEMBL21802003 | 0.88 | LIG1 (0.87) | LIG1MAPTMEN1KMT2ALMNA | |
| SCHEMBL29499085 | 0.88 | LIG1 (0.87) | LIG1MAPTMEN1KMT2ALMNA | |
| SCHEMBL15477907 | 0.87 | LIG1 (0.67) | LIG1MAPTMEN1KMT2ALMNA | |
| Phenol SCHEMBL21603018 | 0.84 | LIG1 (0.81) | LIG1MAPTMEN1KMT2ALMNA | |
| SCHEMBL10611174 | 0.84 | LIG1 (0.62) | LIG1MAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0218366-B1 | POLYESTER POLYMERS OF 3-HYDROXY-4'-(4-HYDROXYPHENYL) BENZOPHENONE OR 3,4'-DIHYDROXYBENZOPHENONE AND DICARBOXYLIC ACIDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-11-22 | — | — | EP | disclosed |
| EP-0218366-A1 | Polyester polymers of 3-hydroxy-4'-(4-hydroxyphenyl) benzophenone or 3,4'-dihydroxybenzophenone and dicarboxylic acids | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-04-15 | — | — | EP | disclosed |
| US-4617369-A | MELT ANISOTROPIC MOLDING MATERIALS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-10-14 | — | — | US | disclosed |