⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31336145 | 0.78 | — | — | |
| SCHEMBL20309958 | 0.75 | — | — | |
| SCHEMBL270796 | 0.73 | — | — | |
| SCHEMBL12533456 | 0.73 | TP53 (0.47) | — | |
| SCHEMBL2269106 | 0.73 | — | — | |
| SCHEMBL2270056 | 0.73 | KDM4E (0.33) | — | |
| Hydrochloric Acid SCHEMBL6105570 | 0.71 | — | — | |
| SCHEMBL18773951 | 0.71 | — | — | |
| SCHEMBL27994898 | 0.71 | — | — | |
| SCHEMBL384164 | 0.69 | TP53 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0184692-B1 | METHOD OF PREPARATION OF O-SILYLATED KETENE ACETALS AND ENOL ETHERS | UNION CARBIDE CORPORATION (US) | 1990-12-27 | — | — | EP | disclosed |
| US-4780554-A | O-silylated ketene acetals and enol ethers and method of preparation | UNION CARBIDE CORPORATION (US) | 1988-10-25 | — | — | US | disclosed |
| EP-0273456-A2 | Vapor phase alcoholysis of aminosilanes and carbamatosilanes | UNION CARBIDE CORPORATION (US) | 1988-07-06 | — | — | EP | disclosed |
| US-4730074-A | Vapor phase alcoholysis of aminosilanes and carbamatosilanes | UNION CARBIDE CORPORATION (US) | 1988-03-08 | — | — | US | disclosed |
| EP-0184692-A1 | Method of preparation of o-silylated ketene acetals and enol ethers | UNION CARBIDE CORPORATION (US) | 1986-06-18 | — | — | EP | disclosed |
| EP-0098911-B1 | IMPROVED PROCESS FOR THE PREPARATION OF OXIMATOHYDRIDOSILANES AND AMINOXYHYDRIDOSILANES | UNION CARBIDE CORPORATION (US) | 1986-04-16 | — | — | EP | disclosed |
| EP-0098911-A1 | Improved process for the preparation of oximatohydridosilanes and aminoxyhydridosilanes | UNION CARBIDE CORPORATION (US) | 1984-01-25 | — | — | EP | disclosed |
| EP-0098912-A1 | Process for the preparation of alkoxyhydridosilanes | UNION CARBIDE CORPORATION (US) | 1984-01-25 | — | — | EP | disclosed |
| US-4395564-A | REACTING AN ALCOHOL WITH SILYL-AMINE | UNION CARBIDE CORPORATION (US) | 1983-07-26 | — | — | US | disclosed |
| US-4384131-A | Process for the preparation of oximatohydridosilanes and aminoxyhydridosilanes | UNION CARBIDE CORPORATION (US) | 1983-05-17 | — | — | US | disclosed |