Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10359288 | 1.00 | BACE1 (0.31) | BACE1 | |
| SCHEMBL10359290 | 1.00 | BACE1 (0.31) | BACE1 | |
| SCHEMBL31267344 | 0.79 | BACE1 (0.34) | BACE1 | |
| SCHEMBL31267343 | 0.79 | BACE1 (0.34) | BACE1 | |
| SCHEMBL6100474 | 0.77 | NPY1R (0.44) | BACE1 | |
| SCHEMBL3605609 | 0.77 | NPY1R (0.41) | BACE1 | |
| SCHEMBL2720938 | 0.76 | BACE1 (0.40) | BACE1 | |
| SCHEMBL10359282 | 0.74 | BACE1 (0.32) | BACE1 | |
| SCHEMBL29772305 | 0.74 | BACE1 (0.32) | BACE1 | |
| SCHEMBL4197153 | 0.73 | MGAM (0.32) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0213547-B1 | CYCLOHEXANEALKANOIC ACIDS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-12-27 | — | — | EP | disclosed |
| US-4622422-A | FOR TREATMENT OF BRONCHIAL ASTHMA | MERRELL DOW PHARMACEUTICALS INC. (US) | 1986-11-11 | — | — | US | disclosed |