Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PTGIR | P43119 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 3/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | PPARD | Q03181 | 3/20 | 0.35 |
| ▸ | PPARA | Q07869 | 3/20 | 0.35 |
| ▸ | TOP1 | P11387 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | FABP4 | P15090 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10360060 | 1.00 | CYSLTR2 (0.36) | CYSLTR2CYSLTR1ALOX5PTGIRTERT | |
| SCHEMBL10360062 | 1.00 | CYSLTR2 (0.36) | CYSLTR2CYSLTR1ALOX5PTGIRTERT | |
| SCHEMBL10359579 | 1.00 | CYSLTR2 (0.36) | CYSLTR2CYSLTR1ALOX5PTGIRTERT | |
| SCHEMBL10359324 | 1.00 | CYSLTR2 (0.36) | CYSLTR2CYSLTR1ALOX5PTGIRTERT | |
| SCHEMBL10359578 | 1.00 | CYSLTR2 (0.36) | CYSLTR2CYSLTR1ALOX5PTGIRTERT | |
| SCHEMBL10359391 | 1.00 | CYSLTR2 (0.36) | CYSLTR2CYSLTR1ALOX5PTGIRTERT | |
| SCHEMBL10915467 | 0.95 | PTGIR (0.39) | ALOX5PTGIRTERTPTPN1PPARG | |
| SCHEMBL10359254 | 0.95 | PTGIR (0.39) | ALOX5PTGIRTERTPTPN1PPARG | |
| SCHEMBL10359252 | 0.95 | PTGIR (0.39) | ALOX5PTGIRTERTPTPN1PPARG | |
| SCHEMBL10915471 | 0.95 | PTGIR (0.39) | ALOX5PTGIRTERTPTPN1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0213547-B1 | CYCLOHEXANEALKANOIC ACIDS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-12-27 | — | — | EP | disclosed |
| EP-0213547-A1 | Cyclohexanealkanoic acids | MERRELL DOW PHARMACEUTICALS INC. (US) | 1987-03-11 | — | — | EP | disclosed |
| US-4622422-A | FOR TREATMENT OF BRONCHIAL ASTHMA | MERRELL DOW PHARMACEUTICALS INC. (US) | 1986-11-11 | — | — | US | disclosed |