Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 13/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10565684 | 0.86 | CYP19A1 (0.40) | HSP90AA1POLBCYP19A1CYP3A4CCR6 | |
| SCHEMBL10360756 | 0.86 | HSP90AA1 (0.46) | HSP90AA1POLBCYP19A1CYP3A4MEN1 | |
| SCHEMBL10565696 | 0.84 | CYP19A1 (0.41) | HSP90AA1POLBCYP19A1CYP3A4CCR6 | |
| SCHEMBL10360981 | 0.83 | HSP90AA1 (0.46) | HSP90AA1CYP19A1CYP3A4KMT2ALMNA | |
| SCHEMBL10361161 | 0.80 | HSP90AA1 (0.46) | HSP90AA1POLBCYP19A1CYP3A4MEN1 | |
| SCHEMBL10361057 | 0.80 | CYP19A1 (0.51) | HSP90AA1POLBCYP19A1CYP3A4MEN1 | |
| SCHEMBL10361515 | 0.80 | CYP19A1 (0.46) | HSP90AA1POLBCYP19A1CYP3A4MEN1 | |
| SCHEMBL10360965 | 0.80 | CCR6 (0.40) | CCR6KCNH2SCN5A | |
| SCHEMBL10362206 | 0.80 | HSP90AA1 (0.62) | HSP90AA1POLBCYP19A1CYP3A4MEN1 | |
| SCHEMBL16731565 | 0.79 | CCR6 (0.39) | CCR6KCNH2SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0158448-B1 | AZOLYL PROPANOLS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-08-29 | — | — | EP | claimed |
| EP-0158448-B1 | AZOLYL PROPANOLS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-08-29 | — | — | EP | disclosed |
| US-4833159-A | FUNGICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-05-23 | — | — | US | disclosed |
| US-4829074-A | INSECTICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-05-09 | — | — | US | disclosed |
| US-4689337-A | 1,2,4-TRIAZOLYL AND PYRAZOLYL GROUPS; FUNGICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-08-25 | — | — | US | disclosed |
| EP-0158448-A2 | Azolyl propanols | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-10-16 | — | — | EP | disclosed |