Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 12/20 | 0.70 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.59 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.59 |
| ▸ | CYP24A1 | Q07973 | 3/20 | 0.48 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.45 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10362269 | 0.99 | CYP19A1 (0.69) | CYP19A1CYP11B1CYP11B2CYP24A1CYP17A1 | |
| SCHEMBL10361919 | 0.88 | CYP24A1 (0.61) | CYP19A1CYP11B1CYP11B2CYP24A1CYP17A1 | |
| Hydrochloric Acid SCHEMBL10362490 | 0.87 | CYP24A1 (0.60) | CYP19A1CYP11B1CYP11B2CYP24A1CYP17A1 | |
| SCHEMBL10362274 | 0.84 | CYP19A1 (0.81) | CYP19A1CYP11B1CYP11B2CYP24A1CYP17A1 | |
| SCHEMBL10362744 | 0.83 | CYP19A1 (0.80) | CYP19A1CYP17A1CYP26A1 | |
| Hydrochloric Acid SCHEMBL10362740 | 0.83 | CYP19A1 (0.79) | CYP19A1CYP11B1CYP11B2CYP24A1CYP17A1 | |
| SCHEMBL10362270 | 0.82 | CYP19A1 (0.78) | CYP19A1CYP24A1CYP17A1CYP26A1 | |
| SCHEMBL6049788 | 0.82 | CYP19A1 (1.00) | CYP19A1CYP24A1CYP17A1CYP26A1 | |
| SCHEMBL10362201 | 0.82 | CYP19A1 (0.78) | CYP19A1CYP11B1CYP11B2CYP17A1CYP26A1 | |
| Hydrochloric Acid SCHEMBL10540492 | 0.82 | CYP19A1 (0.78) | CYP19A1CYP17A1CYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257171-B1 | (BENZOFURAN-2-YL)IMIDAZOLES HAVING PHARMACEUTICAL ACTIVITY, THEIR SALTS AND RELEVANT PRODUCTION PROCESSES | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1990-08-29 | — | — | EP | claimed |
| EP-0257171-A1 | (Benzofuran-2-yl)imidazoles having pharmaceutical activity, their salts and relevant production processes | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1988-03-02 | — | — | EP | claimed |