Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 19/20 | 0.68 |
| ▸ | CYSLTR1 | Q9Y271 | 19/20 | 0.68 |
| ▸ | CTSD | P07339 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ly-163443 SCHEMBL9176125 | 0.92 | CYSLTR2 (0.70) | CYSLTR2CYSLTR1 | |
| SCHEMBL9177875 | 0.92 | CYSLTR2 (0.70) | CYSLTR2CYSLTR1 | |
| Ly-163443 SCHEMBL9505200 | 0.91 | CYSLTR2 (0.69) | CYSLTR2CYSLTR1 | |
| Ly-163443 SCHEMBL9505168 | 0.91 | CYSLTR2 (0.69) | CYSLTR2CYSLTR1 | |
| SCHEMBL9638145 | 0.90 | CYSLTR2 (0.65) | CYSLTR2CYSLTR1CTSD | |
| SCHEMBL10362703 | 0.90 | CYSLTR2 (0.71) | CYSLTR2CYSLTR1CTSD | |
| SCHEMBL9637138 | 0.90 | CYSLTR2 (0.61) | CYSLTR2CYSLTR1CTSD | |
| SCHEMBL9637247 | 0.89 | CYSLTR2 (0.61) | CYSLTR2CYSLTR1CTSD | |
| SCHEMBL9177390 | 0.88 | CYSLTR2 (0.69) | CYSLTR2CYSLTR1CTSD | |
| SCHEMBL10362516 | 0.87 | CYSLTR2 (0.73) | CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0132366-B1 | LEUKOTRIENE ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1990-01-03 | — | — | EP | disclosed |
| EP-0132366-A2 | Leukotriene antagonists | ELI LILLY AND COMPANY (US) | 1985-01-30 | — | — | EP | disclosed |