Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10469643 | 0.92 | GAA (0.59) | GAACDK1MAPTTP53GLA | |
| SCHEMBL119097 | 0.88 | GAA (0.52) | GAACDK1MAPTTP53GLA | |
| SCHEMBL10506007 | 0.88 | TSHR (0.53) | GAACDK1MAPTTP53GLA | |
| SCHEMBL29371340 | 0.88 | GAA (0.52) | GAACDK1MAPTTP53GLA | |
| SCHEMBL10364239 | 0.88 | CDK1 (0.51) | GAACDK1MAPTTP53GLA | |
| SCHEMBL11246536 | 0.85 | CDK1 (0.51) | GAACDK1MAPTTP53GLA | |
| SCHEMBL4887087 | 0.85 | GAA (0.49) | GAACDK1MAPTTP53GLA | |
| SCHEMBL9200551 | 0.85 | GAA (0.53) | GAACDK1MAPTTP53GLA | |
| SCHEMBL10565058 | 0.85 | GAA (0.48) | GAACDK1MAPTTP53GLA | |
| SCHEMBL10363991 | 0.84 | GAA (0.50) | GAACDK1MAPTTP53GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161905-B1 | HERBICIDAL HALOPYRIMIDINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-08-01 | — | — | EP | claimed |
| US-4659361-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-04-21 | — | — | US | claimed |
| EP-0161905-A2 | Herbicidal halopyrimidines | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-11-21 | — | — | EP | claimed |
| EP-0161905-B1 | HERBICIDAL HALOPYRIMIDINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-08-01 | — | — | EP | disclosed |
| US-4659361-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-04-21 | — | — | US | disclosed |
| US-4659361-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-04-21 | — | — | US | disclosed |
| EP-0161905-A2 | Herbicidal halopyrimidines | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-11-21 | — | — | EP | disclosed |