Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 18/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10362706 | 0.90 | ELANE (0.77) | ELANE | |
| SCHEMBL10363043 | 0.89 | ELANE (1.00) | ELANE | |
| SCHEMBL10362693 | 0.89 | ELANE (1.00) | ELANE | |
| SCHEMBL10362684 | 0.89 | ELANE (1.00) | ELANE | |
| SCHEMBL10362845 | 0.85 | ELANE (0.70) | ELANE | |
| SCHEMBL10363504 | 0.85 | ELANE (0.70) | ELANE | |
| SCHEMBL8700258 | 0.84 | ELANE (0.82) | ELANE | |
| SCHEMBL8702543 | 0.84 | ELANE (0.82) | ELANE | |
| SCHEMBL6498121 | 0.83 | ELANE (0.80) | ELANE | |
| SCHEMBL10362907 | 0.83 | ELANE (0.66) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0147211-B1 | 4H-3,1-BENZOXAZIN-4-ONES AND RELATED COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | SYNTEX (U.S.A.) INC. (US) | 1990-09-12 | — | — | EP | disclosed |
| US-4657893-A | ANTIINFLAMMATORY AGENTS | SYNTEX (U.S.A.) INC. (US) | 1987-04-14 | — | — | US | disclosed |
| EP-0147211-A2 | 4H-3,1-benzoxazin-4-ones and related compounds, pharmaceutical compositions containing them, and processes for their preparation | SYNTEX (U.S.A.) INC. (US) | 1985-07-03 | — | — | EP | disclosed |