Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.48 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3042205 | 1.00 | LPAR3 (0.48) | LPAR3LPAR2TSHRMAPTABCC4 | |
| SCHEMBL4300522 | 1.00 | LPAR3 (0.48) | LPAR3LPAR2TSHRMAPTABCC4 | |
| SCHEMBL95153 | 0.98 | — | — | |
| SCHEMBL96094 | 0.91 | — | — | |
| SCHEMBL98184 | 0.80 | — | — | |
| SCHEMBL7116385 | 0.74 | — | — | |
| SCHEMBL3024776 | 0.74 | LPAR2 (0.34) | LPAR3LPAR2MAPTLMNAUSP2 | |
| SCHEMBL3038091 | 0.74 | LPAR2 (0.34) | LPAR3LPAR2MAPTLMNAUSP2 | |
| SCHEMBL153995 | 0.73 | — | — | |
| SCHEMBL2286288 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207097-B1 | NEW CARBONIC ACID ESTERS | CIBA-GEIGY AG (CH) | 1990-08-08 | — | — | EP | disclosed |
| US-4764523-A | Novel carbonic acid esters | CIBA-GEIGY CORPORATION (US) | 1988-08-16 | — | — | US | disclosed |
| EP-0207097-A1 | NEW CARBONIC ACID ESTERS. | CIBA GEIGY AG (CH) | 1987-01-07 | — | — | EP | disclosed |
| WO-1986003747-A1 | NEW CARBONIC ACID ESTERS | CIBA-GEIGY AG (CH) | 1986-07-03 | — | — | WO | disclosed |
| US-4202816-A | ENOL-PIPERIDINE METAL COMPLEXES | CIBA-GEIGY CORPORATION (US) | 1980-05-13 | — | — | US | disclosed |