Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12418678 | 0.96 | MEN1 (0.56) | MEN1KMT2ATDP1MAPTHSP90AA1 | |
| SCHEMBL12418543 | 0.94 | MEN1 (0.58) | MEN1KMT2ATDP1MAPTHSP90AA1 | |
| SCHEMBL12394779 | 0.88 | MEN1 (0.76) | MEN1KMT2ATDP1MAPTHSP90AA1 | |
| SCHEMBL12394776 | 0.86 | KMT2A (0.60) | MEN1KMT2ATDP1MAPTHSP90AA1 | |
| SCHEMBL10368769 | 0.85 | MEN1 (0.76) | MEN1KMT2ATDP1MAPTHSP90AA1 | |
| SCHEMBL1969687 | 0.85 | KMT2A (0.52) | MEN1KMT2ATDP1MAPTHSP90AA1 | |
| SCHEMBL12394775 | 0.84 | MEN1 (0.56) | MEN1KMT2ATDP1MAPTHSP90AA1 | |
| SCHEMBL1964298 | 0.84 | MEN1 (0.57) | MEN1KMT2ATDP1MAPTHSP90AA1 | |
| SCHEMBL12418677 | 0.84 | MEN1 (0.74) | MEN1KMT2ATDP1MAPTHSP90AA1 | |
| SCHEMBL10915818 | 0.83 | MEN1 (0.51) | MEN1KMT2ATDP1MAPTHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129186-B1 | AZOLE DERIVATIVES | BASF Aktiengesellschaft (DE) | 1990-08-16 | — | — | EP | disclosed |
| EP-0129186-A2 | Azole derivatives | BASF Aktiengesellschaft (DE) | 1984-12-27 | — | — | EP | disclosed |