Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 7/20 | 0.62 |
| ▸ | HTR2C | P28335 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | PPARG | P37231 | 2/20 | 0.60 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.60 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.60 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.60 |
| ▸ | ALB | P02768 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | PGR | P06401 | 4/20 | 0.54 |
| ▸ | DAO | P14920 | 1/20 | 0.53 |
| ▸ | SNCA | P37840 | 1/20 | 0.53 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.53 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | APEX1 | P27695 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8988389 | 1.00 | NR1I2 (0.62) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL8759176 | 1.00 | NR1I2 (0.62) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL8351189 | 1.00 | NR1I2 (0.62) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL9573660 | 0.94 | NR1I2 (0.63) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL9573654 | 0.94 | NR1I2 (0.63) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL10861182 | 0.94 | NR1I2 (0.63) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL9844207 | 0.94 | NR1I2 (0.63) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL9826590 | 0.94 | NR1I2 (0.63) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL10337520 | 0.94 | NR1I2 (0.63) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL10337581 | 0.94 | NR1I2 (0.63) | NR1I2HTR2CMAPTPPARGSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0121244-B1 | CEPHALOSPORIN DERIVATIVES | Bristol-Myers Company (US) | 1990-09-12 | — | — | EP | disclosed |
| EP-0097961-B1 | CEPHALOSPORIN DERIVATIVES, A PROCESS FOR THE MANUFACTURE THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | Bristol-Myers Company (US) | 1987-11-11 | — | — | EP | disclosed |
| US-4525473-A | BACTERICIDES | BRISTOL-MYERS COMPANY (US) | 1985-06-25 | — | — | US | disclosed |
| US-4507487-A | CHEMICAL INTERMEDIATES FOR CEPHALOSPORINS | BRISTOL-MYERS COMPANY (US) | 1985-03-26 | — | — | US | disclosed |
| US-4500526-A | ANTIBIOTICS, BACTERICIDES | BRISTOL-MYERS COMPANY (US) | 1985-02-19 | — | — | US | disclosed |
| US-4486586-A | BACTERICIDAL ANTIBIOTICS | BRISTOL-MYERS COMPANY (US) | 1984-12-04 | — | — | US | disclosed |
| EP-0121244-A2 | Cephalosporin derivatives | Bristol-Myers Company (US) | 1984-10-10 | — | — | EP | disclosed |
| US-4457929-A | BACTERICIDES | BRISTOL-MYERS COMPANY (US) | 1984-07-03 | — | — | US | disclosed |
| US-4406899-A | Cephalosporins | BRISTOL-MYERS COMPANY (US) | 1983-09-27 | — | — | US | disclosed |