Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10366514 | 1.00 | NPSR1 (0.35) | NPSR1MAPTMEN1KMT2ALMNA | |
| SCHEMBL13483655 | 0.92 | NPSR1 (0.34) | NPSR1MAPTMEN1KMT2ALMNA | |
| SCHEMBL9096545 | 0.90 | MAPT (0.33) | NPSR1MAPTMEN1KMT2ALMNA | |
| SCHEMBL9096558 | 0.90 | MAPT (0.33) | NPSR1MAPTMEN1KMT2ALMNA | |
| SCHEMBL13483594 | 0.90 | MAPT (0.35) | NPSR1MAPTMEN1KMT2ALMNA | |
| SCHEMBL9096550 | 0.90 | MAPT (0.33) | NPSR1MAPTMEN1KMT2ALMNA | |
| SCHEMBL9096298 | 0.89 | MAPT (0.34) | NPSR1MAPTMEN1KMT2ALMNA | |
| SCHEMBL9096299 | 0.89 | MAPT (0.34) | NPSR1MAPTMEN1KMT2ALMNA | |
| SCHEMBL12427261 | 0.89 | MAPT (0.34) | NPSR1MAPTMEN1KMT2ALMNA | |
| SCHEMBL13744334 | 0.89 | MAPT (0.34) | NPSR1MAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0191185-B1 | QUINOLINE-CARBOXYLIC ACID DERIVATIVES | DAIICHI SEIYAKU CO., LTD. (JP) | 1990-03-07 | — | — | EP | disclosed |
| EP-0191185-A1 | Quinoline-carboxylic acid derivatives | DAIICHI SEIYAKU CO., LTD. (JP) | 1986-08-20 | — | — | EP | disclosed |