Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | TRPC1 | P48995 | 2/20 | 0.53 |
| ▸ | TRPC3 | Q13507 | 2/20 | 0.53 |
| ▸ | STIM1 | Q13586 | 2/20 | 0.53 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.53 |
| ▸ | STIM2 | Q9P246 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | HPGD | P15428 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21604814 | 0.91 | MAPT (0.57) | MAPTTRPC1TRPC3STIM1ORAI1 | |
| SCHEMBL20265798 | 0.90 | KDM4E (0.56) | MAPTTRPC1TRPC3STIM1ORAI1 | |
| SCHEMBL30147880 | 0.90 | KDM4E (0.56) | MAPTTRPC1TRPC3STIM1ORAI1 | |
| SCHEMBL21605015 | 0.84 | TRPC1 (0.53) | MAPTTRPC1TRPC3STIM1ORAI1 | |
| SCHEMBL30147969 | 0.84 | TRPC1 (0.53) | MAPTTRPC1TRPC3STIM1ORAI1 | |
| SCHEMBL10678549 | 0.84 | HTT (0.55) | MAPTHTTKDM4EHPGDALDH1A1 | |
| SCHEMBL2325526 | 0.84 | MAPT (0.76) | MAPTTRPC1TRPC3STIM1ORAI1 | |
| SCHEMBL21604976 | 0.83 | MAPT (0.56) | MAPTTRPC1TRPC3STIM1ORAI1 | |
| SCHEMBL31117084 | 0.83 | HTT (0.69) | MAPTHTTHPGDALDH1A1MEN1 | |
| SCHEMBL2299638 | 0.82 | SMN1; SMN2 (0.57) | MAPTKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0151866-B1 | HERBICIDAL PYRAZOLE-(THIO)-CARBOXAMIDES | ELI LILLY AND COMPANY (US) | 1990-07-25 | — | — | EP | disclosed |
| US-4620865-A | Herbicidal and algicidal 1,5-disubstituted-1H-pyrazole-4-carboxamides | ELI LILLY AND COMPANY (US) | 1986-11-04 | — | — | US | disclosed |
| EP-0151866-A2 | Herbicidal pyrazole-(thio)-carboxamides | ELI LILLY AND COMPANY (US) | 1985-08-21 | — | — | EP | disclosed |