Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A3 | Q92570 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10365996 | 0.87 | NR4A3 (0.42) | NR4A3SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL3291164 | 0.86 | NR4A3 (0.44) | NR4A3SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL3294253 | 0.82 | NR4A3 (0.54) | NR4A3SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL3293316 | 0.82 | NR4A3 (0.38) | NR4A3SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL14413274 | 0.81 | NR4A3 (0.42) | NR4A3SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL1406916 | 0.78 | NR4A3 (0.40) | NR4A3SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL1406669 | 0.76 | NR4A3 (0.41) | NR4A3SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL15750714 | 0.75 | KDM4E (0.37) | NR4A3SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL3293045 | 0.75 | NR4A3 (0.38) | NR4A3SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL574333 | 0.73 | KDM4E (0.44) | NR4A3SMN1; SMN2KDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0151867-B1 | CYANOPYRAZOLE HERBICIDES | ELI LILLY AND COMPANY (US) | 1990-01-10 | — | — | EP | disclosed |