Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | APAF1 | O14727 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.39 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | FAP | Q12884 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10369029 | 1.00 | KCNH2 (0.49) | KCNH2TDP1APAF1LMNATSHR | |
| SCHEMBL10370472 | 0.91 | KCNH2 (0.52) | KCNH2TDP1APAF1LMNATSHR | |
| SCHEMBL10370471 | 0.91 | KCNH2 (0.52) | KCNH2TDP1APAF1LMNATSHR | |
| SCHEMBL10530068 | 0.91 | KCNH2 (0.49) | KCNH2TDP1APAF1LMNATSHR | |
| SCHEMBL10530073 | 0.91 | KCNH2 (0.49) | KCNH2TDP1APAF1LMNATSHR | |
| SCHEMBL10824145 | 0.89 | KCNH2 (0.57) | KCNH2TDP1APAF1LMNATSHR | |
| SCHEMBL10824146 | 0.89 | KCNH2 (0.57) | KCNH2TDP1APAF1LMNATSHR | |
| SCHEMBL10367199 | 0.88 | TDP1 (0.42) | KCNH2TDP1APAF1LMNATSHR | |
| SCHEMBL10367196 | 0.88 | TDP1 (0.42) | KCNH2TDP1APAF1LMNATSHR | |
| SCHEMBL10667776 | 0.88 | KCNH2 (0.52) | KCNH2TDP1APAF1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0111281-B1 | NEW CEPHEM COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-06-06 | — | — | EP | disclosed |
| US-4719206-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-01-12 | — | — | US | disclosed |
| US-4584290-A | MICROBIOCIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-04-22 | — | — | US | disclosed |