Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | VHL | P40337 | 1/20 | 0.38 |
| ▸ | ELOC | Q15369 | 1/20 | 0.38 |
| ▸ | ELOB | Q15370 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10369273 | 1.00 | MAOB (0.51) | MAOBKDM4EMIFS100A4MAOA | |
| SCHEMBL11492158 | 0.87 | KDM4E (0.55) | MAOBKDM4EMIFS100A4MAOA | |
| SCHEMBL11492156 | 0.87 | KDM4E (0.55) | MAOBKDM4EMIFS100A4MAOA | |
| SCHEMBL10060190 | 0.76 | KDM4E (0.54) | MAOBKDM4EMIFS100A4VHL | |
| SCHEMBL11485212 | 0.76 | MIF (0.65) | MAOBKDM4EMIFS100A4MAOA | |
| SCHEMBL11485209 | 0.76 | MIF (0.65) | MAOBKDM4EMIFS100A4MAOA | |
| SCHEMBL9159671 | 0.75 | VHL (0.49) | MAOBKDM4ES100A4VHLELOC | |
| SCHEMBL567151 | 0.74 | KDM4E (0.55) | MAOBKDM4EMIFS100A4VHL | |
| SCHEMBL567153 | 0.74 | KDM4E (0.55) | MAOBKDM4EMIFS100A4VHL | |
| SCHEMBL567875 | 0.74 | KDM4E (0.55) | MAOBKDM4EMIFS100A4VHL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0196803-B1 | BENZENE-FUSED HETEROCYCLIC COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-12-12 | — | — | EP | disclosed |
| US-4692444-A | DIURETICS, VASODILATORS, HYPOTENSIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-09-08 | — | — | US | disclosed |
| EP-0196803-A2 | Benzene-fused heterocyclic compound | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-08 | — | — | EP | disclosed |